A study has found that chemicals in hundreds of everyday items gather in the liver, which can cause serious health problems.
Per- and polyfluoroalkyl substances, also known as PFAs, are man-made chemicals used to make products water, stain and grease-resistant.
They are also called 'forever chemicals' because they break down very slowly, causing them to build up in the body over time.
PFAs have been linked to a long list of health conditions, including cancer, asthma, raised cholesterol, high blood pressure and thyroid disease.
The study found evidence the chemicals build up in the liver, where they can cause disease.
“Experimental evidence indicates that exposure to per-and polyfluorinated substances (PFAS), a class of endocrine-disrupting chemicals, has the ability to promote metabolic changes that can result in fatty liver,” said the authors of the study, which was published in Environmental Health Perspectives.
Fatty liver disease is caused by the storage of extra fat in the liver. It does not cause a serious issue in everyone, but it can lead to liver damage.
“The stable chemical properties that make PFAs ideal for industrial use also allow them to persist and accumulate in the environment, which is of concern because of the potential for long-term human health effects," the authors said. The study was led by researchers at the University of Southern California, Los Angeles.
With thousands of types of PFAs, almost everyone is exposed to them at some stage.
Previous studies have shown PFAs are present in the blood and all the body organs tested, including the heart, liver, bones and muscle.
“These chemicals can cause liver and kidney damage, impair male fertility, affect hormones such as oestrogen, testosterone and cortisol,” said Dr Aswin Pankajakshan, specialist in endocrinology, diabetology and metabolic disorders at NMC Royal Hospital in Dubai.
Significant sources of exposure include unfiltered drinking water, as well as food, the air and early life placental or breast milk, experts said.
“It can go to any gland and cause many problems,” said Dr Ihab El Tayeb, consultant in endocrinology at International Modern Hospital Dubai.
“It can affect foetal development during pregnancy, because it is in food and beverages consumed. It’s also in canned food. That’s why we are all exposed.”
Limit exposure
People can limit their exposure by washing fruit and vegetables before eating them, and choosing organic produce, if possible.
Non-stick pans should be replaced with ceramic-coated cookware.
“Do not use microwaves [so] much, especially with plastic food containers,” said Dr El Tayeb.
“Also avoid canned and processed food if you can. And make most of your food at home. Use a water filter if you can.”
Experts say they pose a problem because they can mimic natural hormones in the body.
“Usually natural hormones work by going to a receptor in a specific organ and then their work starts,” said Dr El Tayeb.
“This endocrine disruptors, sometimes it mimics the hormones. It is cheating the body.
"So they go to the receptor to work instead of the original hormone. And when the natural hormone comes it cannot work.”
A separate study, published in the Environmental Science and Technology journal, found about 60 per cent of children's clothing, fabrics used in pillows, bedding and furniture, sometimes even with green certification, were found to contain PFAs.
Potential health effects of PFAs
PFAs have been used in many products worldwide since the 1950s, according to The Centres for Disease Control and Prevention.
PFOA (perfluorooctanoic acid) and PFOS (perfluorooctanesulfonic acid) are probably the best known, said Dr Pankajakshan.
PTFE (polytetrafluoroethylene) is used as a coating for non-stick pots and pots. When heated at high temperatures, utensils coated in the substance release toxic fumes that cause mild to severe toxicity.
“PTFE is also found to be having carcinogenic potential and also disrupt hormonal balance and affect foetal development,” Dr Pankajakshan said.
PFOA is used in carpeting, upholstery, apparel, floor wax, textiles and firefighting foam. It resists heat, water, stains and grease. It lasts a long time, even in people. Studies have shown high levels of exposure may cause testicular and kidney cancer.
PFOS is used to make Scotchguard water repellent. The chemical has been shown to be toxic to fertility, the thyroid, the immune system and kidneys in laboratory animals and in vitro human systems.
Mercer, the investment consulting arm of US services company Marsh & McLennan, expects its wealth division to at least double its assets under management (AUM) in the Middle East as wealth in the region continues to grow despite economic headwinds, a company official said.
Mercer Wealth, which globally has $160 billion in AUM, plans to boost its AUM in the region to $2-$3bn in the next 2-3 years from the present $1bn, said Yasir AbuShaban, a Dubai-based principal with Mercer Wealth.
“Within the next two to three years, we are looking at reaching $2 to $3 billion as a conservative estimate and we do see an opportunity to do so,” said Mr AbuShaban.
Mercer does not directly make investments, but allocates clients’ money they have discretion to, to professional asset managers. They also provide advice to clients.
“We have buying power. We can negotiate on their (client’s) behalf with asset managers to provide them lower fees than they otherwise would have to get on their own,” he added.
Mercer Wealth’s clients include sovereign wealth funds, family offices, and insurance companies among others.
From its office in Dubai, Mercer also looks after Africa, India and Turkey, where they also see opportunity for growth.
Wealth creation in Middle East and Africa (MEA) grew 8.5 per cent to $8.1 trillion last year from $7.5tn in 2015, higher than last year’s global average of 6 per cent and the second-highest growth in a region after Asia-Pacific which grew 9.9 per cent, according to consultancy Boston Consulting Group (BCG). In the region, where wealth grew just 1.9 per cent in 2015 compared with 2014, a pickup in oil prices has helped in wealth generation.
BCG is forecasting MEA wealth will rise to $12tn by 2021, growing at an annual average of 8 per cent.
Drivers of wealth generation in the region will be split evenly between new wealth creation and growth of performance of existing assets, according to BCG.
Another general trend in the region is clients’ looking for a comprehensive approach to investing, according to Mr AbuShaban.
“Institutional investors or some of the families are seeing a slowdown in the available capital they have to invest and in that sense they are looking at optimizing the way they manage their portfolios and making sure they are not investing haphazardly and different parts of their investment are working together,” said Mr AbuShaban.
Some clients also have a higher appetite for risk, given the low interest-rate environment that does not provide enough yield for some institutional investors. These clients are keen to invest in illiquid assets, such as private equity and infrastructure.
“What we have seen is a desire for higher returns in what has been a low-return environment specifically in various fixed income or bonds,” he said.
“In this environment, we have seen a de facto increase in the risk that clients are taking in things like illiquid investments, private equity investments, infrastructure and private debt, those kind of investments were higher illiquidity results in incrementally higher returns.”
The Abu Dhabi Investment Authority, one of the largest sovereign wealth funds, said in its 2016 report that has gradually increased its exposure in direct private equity and private credit transactions, mainly in Asian markets and especially in China and India. The authority’s private equity department focused on structured equities owing to “their defensive characteristics.”
THE BIO
Born: Mukalla, Yemen, 1979
Education: UAE University, Al Ain
Family: Married with two daughters: Asayel, 7, and Sara, 6
Favourite piece of music: Horse Dance by Naseer Shamma
Favourite book: Science and geology
Favourite place to travel to: Washington DC
Best advice you’ve ever been given: If you have a dream, you have to believe it, then you will see it.
Sarfira
Director: Sudha Kongara Prasad
Starring: Akshay Kumar, Radhika Madan, Paresh Rawal
Rating: 2/5
Zayed Sustainability Prize
500 People from Gaza enter France
115 Special programme for artists
25 Evacuation of injured and sick
Electoral College Victory
Trump has so far secured 295 Electoral College votes, according to the Associated Press, exceeding the 270 needed to win. Only Nevada and Arizona remain to be called, and both swing states are leaning Republican. Trump swept all five remaining swing states, North Carolina, Georgia, Pennsylvania, Michigan and Wisconsin, sealing his path to victory and giving him a strong mandate.
Popular Vote Tally
The count is ongoing, but Trump currently leads with nearly 51 per cent of the popular vote to Harris’s 47.6 per cent. Trump has over 72.2 million votes, while Harris trails with approximately 67.4 million.
MOUNTAINHEAD REVIEW
Starring: Ramy Youssef, Steve Carell, Jason Schwartzman
Director: Jesse Armstrong
Rating: 3.5/5
If you go
The flights Etihad (www.etihad.com) and Spice Jet (www.spicejet.com) fly direct from Abu Dhabi and Dubai to Pune respectively from Dh1,000 return including taxes. Pune airport is 90 minutes away by road.
The hotels A stay at Atmantan Wellness Resort (www.atmantan.com) costs from Rs24,000 (Dh1,235) per night, including taxes, consultations, meals and a treatment package.
UPI facts
More than 2.2 million Indian tourists arrived in UAE in 2023
More than 3.5 million Indians reside in UAE
Indian tourists can make purchases in UAE using rupee accounts in India through QR-code-based UPI real-time payment systems
Indian residents in UAE can use their non-resident NRO and NRE accounts held in Indian banks linked to a UAE mobile number for UPI transactions
UK-EU trade at a glance
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Co-operation on security initiatives and procurement of defence products
Youth experience scheme to work, study or volunteer in UK and EU countries
Smoother border management with use of e-gates
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