Israeli forces launched a third day of operations Monday around the flashpoint West Bank city of Jenin after heavy gun battles in recent days and overnight arrests, the army said.
Tensions have soared since attacks in Israel killed 14 people in the past three weeks, with Prime Minister Naftali Bennett warning the state is now "on the offensive".
The Israeli army said 14 Palestinians were arrested early Monday, a day after four Palestinians were killed in separate incidents in the occupied territory, sparking criticism from international observers.
Another 13 army battalions are operating in the West Bank, a military source said.
In Jenin, thousands of mourners flooded the streets, many carrying Palestinian flags or rifles, for the funeral of Mohamed Zakarneh, 17, who died of gunshot wounds overnight.
"The resistance is in direct confrontation with the occupation and any minute we must expect a total clash," said Ziad Al Nakhala, secretary general of the militant Islamic Jihad movement.
"Jenin must not be isolated, no matter the cost."
The Israeli army said it operated on Monday in Burqa and Qallil in the northern West Bank, as well as in Al Aroub and Hebron in the south.
"Violent riots were instigated by dozens of Palestinians" near Nablus, the army said, while the Palestine Red Crescent said 24 Palestinians were wounded in Nablus overnight.
Jenin, as well as Bethlehem in the southern West Bank, declared general strikes, shutting shops, offices and official institutions.
"We will beat this terror wave with our powerful security forces," Israeli Defence Minister Benny Gantz said on Monday.
"There is the risk of escalation into a wider campaign in Gaza or some events in Lebanon."
Tension has surged during Ramadan, nearly a year after violence flared in the Hamas-ruled Gaza Strip, leading to 11 days of war.
Fourteen people in Israel have been killed in four attacks since March 22, including a shooting spree in Bnei Brak, an Orthodox Jewish city in greater Tel Aviv, carried out by a Palestinian from Jenin.
Over the same period, at least 14 Palestinians have been killed, including assailants, AFP reported.
Two of them were women shot dead on Sunday.
Maha Zaatari stabbed and lightly wounded an officer in Hebron before she was killed.
Ghada Sabatien was unarmed but failed to heed soldiers' warnings to stop near Bethlehem, the army said.
The British consulate general in Jerusalem on Monday sent condolences to her family and wrote that "a swift, thorough investigation" into her death was needed.
The Israeli military source said 30 Palestinian suspects were apprehended in the past few days, and 16 attacks against Israeli targets foiled.
Islamic Jihad has been growing in strength and capability in Gaza and the West Bank, and especially in Jenin, the Israeli military source said.
The source said Israeli forces are operating in Jenin partially because the Palestinian Authority — which has a security co-ordination agreement with Israel — has failed in the area.
Israeli troops were targeting relatives of Raad Hazem, 28, a Jenin man who last Thursday killed three Israeli civilians and wounded more than a dozen at a Tel Aviv bar before he was shot dead after a manhunt.
The Israeli army demanded the father hand himself in before a planned demolition of his family's home.
It said it had engaged in an exchange of gunfire involving the assailant's family members on Sunday, the clash in which Zakarneh was killed.
Another Palestinian from the Bethlehem area was shot dead on Sunday after hurling a Molotov cocktail at an Israeli vehicle, AFP reported.
In another incident overnight, two Israelis were shot and wounded after entering Nablus, where the previous night Joseph's tomb, a religious site, was vandalised by Palestinians.
"A group of Israeli civilians entered into the city after breaking through an unmanned military checkpoint," the army said.
Shortly after, it said, the two Israeli men emerged at another checkpoint "with gunshot wounds".
One of the men involved told public broadcaster Kan they had gone to inspect Joseph's tomb.
"We were done and heading back to Jerusalem but then we took a wrong turn" and were shot at by a "terrorist", he said.