Despite being commonly perceived as a mild illness, chickenpox can lead to death in severe cases. Getty Images
Despite being commonly perceived as a mild illness, chickenpox can lead to death in severe cases. Getty Images
Despite being commonly perceived as a mild illness, chickenpox can lead to death in severe cases. Getty Images
Despite being commonly perceived as a mild illness, chickenpox can lead to death in severe cases. Getty Images

Scientists recommend chickenpox vaccine for children in Britain's NHS


Marwa Hassan
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The chickenpox vaccine should be introduced for children in Britain's publicly funded healthcare system, scientists have told the government.

The vaccine should be given to children aged 12 to 18 months in the National Health Service, the Joint Committee on Vaccination and Immunisation said.

It added that the vaccine, also known as the varicella shot, should be administered in two doses, at 12 months and then at 18 months.

The recommendations are supported by data from other countries, where the vaccine has significantly reduced the prevalence of chickenpox and prevented most severe cases in children.

The JCVI suggested a temporary catch-up programme for older children who miss the initial vaccination age.

Officials in the Department of Health and Social Care were reviewing the recommendation.

University of Oxford studies found that two doses of the vaccine – given as two separate injections at least four weeks apart – give about 98 per cent protection in children and about 75 per cent protection in teenagers and adults.

Historically, the NHS has been hesitant to introduce the chickenpox vaccine, citing concerns that it might increase the risk of chickenpox and shingles in adults.

The underlying reasoning was that vaccination would prevent childhood infection, potentially leading to more severe cases in unvaccinated adults.

However, there has been a shift in perspective based on new data and international experiences.

Prof Sir Andrew Pollard, chairman of the JCVI, emphasised the seriousness of chickenpox, particularly in babies, younger children, and adults.

“Chickenpox is well known, and most parents will probably consider it a common and mild illness among children,” he said.

“But for some babies, young children and even adults, chickenpox or its complications can be very serious, resulting in hospitalisation and even death.”

Adding the varicella vaccine to the childhood immunisation programme will dramatically reduce the number of chickenpox cases in the community, Prof Pollard said, leading to far fewer of the more serious cases.

“We now have decades of evidence from the US and other countries showing that introducing this programme is safe, effective and will have a really positive impact on the health of young children,” he said.

What is chickenpox?

Chickenpox, caused by the varicella-zoster virus, is an acute and highly contagious disease.

Up to 90 per cent of non-immune individuals in close contact with an infected person are at risk of infection.

The disease begins with mild fever and headaches, followed by a rash that develops into itchy fluid-filled blisters. The virus spreads through direct contact with the rash, airborne droplets, or infected items like clothing.

Symptoms typically appear 14 to 21 days after infection. Infectiousness peaks one to two days before the rash and continues until all blisters crust over.

After chickenpox infection, the virus can remain dormant in the nervous system and reactivate years later as shingles (herpes zoster).

It mostly affects children under 10 and spreads rapidly in close-contact settings like schools.

While usually mild in children, chickenpox can be more severe in adolescents, adults, and specific groups like newborns, pregnant women, and the immunocompromised.

Possible complications include pneumonia, secondary bacterial infections, encephalitis, and in rare cases, death.

In pregnant women, varicella infection can lead to severe chickenpox and congenital varicella syndrome in the foetus, causing limb deformities, skin scarring, cataracts, and growth retardation.

Symptom management mainly involves reducing fever and itchiness.

Antiviral drugs and immunoglobulin are available for high-risk individuals to prevent severe illness.

Chickenpox is endemic worldwide, with peak outbreaks in winter and spring in temperate climates.

By age 15, nine out of 10 people in the UK have had chickenpox.

Two vaccines are licensed in the UK. Vaccination is advised for children close to high-risk individuals and non-immune healthcare workers.

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Mercer, the investment consulting arm of US services company Marsh & McLennan, expects its wealth division to at least double its assets under management (AUM) in the Middle East as wealth in the region continues to grow despite economic headwinds, a company official said.

Mercer Wealth, which globally has $160 billion in AUM, plans to boost its AUM in the region to $2-$3bn in the next 2-3 years from the present $1bn, said Yasir AbuShaban, a Dubai-based principal with Mercer Wealth.

Within the next two to three years, we are looking at reaching $2 to $3 billion as a conservative estimate and we do see an opportunity to do so,” said Mr AbuShaban.

Mercer does not directly make investments, but allocates clients’ money they have discretion to, to professional asset managers. They also provide advice to clients.

“We have buying power. We can negotiate on their (client’s) behalf with asset managers to provide them lower fees than they otherwise would have to get on their own,” he added.

Mercer Wealth’s clients include sovereign wealth funds, family offices, and insurance companies among others.

From its office in Dubai, Mercer also looks after Africa, India and Turkey, where they also see opportunity for growth.

Wealth creation in Middle East and Africa (MEA) grew 8.5 per cent to $8.1 trillion last year from $7.5tn in 2015, higher than last year’s global average of 6 per cent and the second-highest growth in a region after Asia-Pacific which grew 9.9 per cent, according to consultancy Boston Consulting Group (BCG). In the region, where wealth grew just 1.9 per cent in 2015 compared with 2014, a pickup in oil prices has helped in wealth generation.

BCG is forecasting MEA wealth will rise to $12tn by 2021, growing at an annual average of 8 per cent.

Drivers of wealth generation in the region will be split evenly between new wealth creation and growth of performance of existing assets, according to BCG.

Another general trend in the region is clients’ looking for a comprehensive approach to investing, according to Mr AbuShaban.

“Institutional investors or some of the families are seeing a slowdown in the available capital they have to invest and in that sense they are looking at optimizing the way they manage their portfolios and making sure they are not investing haphazardly and different parts of their investment are working together,” said Mr AbuShaban.

Some clients also have a higher appetite for risk, given the low interest-rate environment that does not provide enough yield for some institutional investors. These clients are keen to invest in illiquid assets, such as private equity and infrastructure.

“What we have seen is a desire for higher returns in what has been a low-return environment specifically in various fixed income or bonds,” he said.

“In this environment, we have seen a de facto increase in the risk that clients are taking in things like illiquid investments, private equity investments, infrastructure and private debt, those kind of investments were higher illiquidity results in incrementally higher returns.”

The Abu Dhabi Investment Authority, one of the largest sovereign wealth funds, said in its 2016 report that has gradually increased its exposure in direct private equity and private credit transactions, mainly in Asian markets and especially in China and India. The authority’s private equity department focused on structured equities owing to “their defensive characteristics.”

Updated: November 14, 2023, 1:16 PM