Twitter has made the transfer of power, migrating the @POTUS and @VP handles from Donald Trump and Mike Pence to Joe Biden and Kamala Harris.
The new president tweeted shortly after taking the oath of office, saying he was getting “right to work”.
Ms Harris also kept her first message short and to just three words.
The @FLOTUS account of the first lady also changed over to Jill Biden.
Institutional accounts on social media are held by the person in office.
But, unlike when the accounts transferred from the administration of Barack Obama to that of Mr Trump and retained all the followers, Mr Biden was handed a blank slate.
The official @POTUS account had only one million followers on Wednesday when Mr Biden spoke on the platform outside the Capitol building. Most of those followers were those who joined his transition account this week.
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US President Joe Biden speaks during the 59th Presidential inauguration in Washington. Reuters -
President Joe Biden signs executive orders in the Oval Office of the White House. Reuters -
President Joe Biden swears in presidential appointees in a virtual ceremony in the State Dining Room of the White House. Reuters -
President Joe Biden and first lady Jill Biden wave as they arrive at the North Portico of the White House. AP Photo -
President Joe Biden and his wife Jill embrace as they arrive to the White House. Reuters -
President Joe Biden and first lady Jill Biden walk up the stairs as they arrive at the North Portico of the White House. AP Photo -
President Joe Biden, First Lady Jill Biden and family, walk in front of the White House. AP Photo -
President Joe Biden and Vice President Kamala Harris participate in a wreath laying ceremony at the Tomb of the Unknown Soldier at Arlington National Cemetery. AP Photo -
Former President Bill Clinton with his wife, former Secretary of State, Hillary Clinton, former President George W. Bush with his wife Laura Bush, and former president Barack Obama and his wife Michelle Obama at the Arlington National Cemetery. Reuters -
US President Joe Biden, first lady Jill Biden, Vice President Kamala Harris, and her husband Doug Emhoff look on as they leave the US Capitol after the inauguration ceremony. Reuters -
US President Joe Biden signs documents in the President's Room at the US Capitol following the inauguration ceremony. Bloomberg -
Vice President Kamala Harris and her husband Doug Emhoff, wave from the Capitol steps as former Vice President Mike Pence's motorcade departs. AP Photo -
US President Joe Biden speaks during the 59th Presidential inauguration in Washington. Reuters -
US President-elect Joe Biden is sworn in as the 46th president of the United States during the 59th presidential inauguration in Washington. Bloomberg -
Joe Biden is sworn in as the 46th President of the United States as his spouse Jill Biden holds a bible on the West Front of the Capitol in Washington, DC. Reuters -
Kamala Harris is sworn in as vice president by Supreme Court Justice Sonia Sotomayor as her husband Doug Emhoff holds the Bible during the 59th Presidential Inauguration at the US Capitol in Washington, DC. AP -
Social distancing audience during the inauguration of Joe Biden as the 46th President of the United States. Reuters -
Lady Gaga sings the National Anthem at the inauguration of US President-elect Joe Biden. AFP -
Lady Gaga sings the National Anthem as US Vice President Mike Pence and Vice President-elect Kamala Harris look on. Reuters -
From left: Doug Emhoff, US Vice President-elect Kamala Harris, incoming US First Lady Jill Biden, US President-elect Joe Biden arrive for the inauguration of Joe Biden as the 46th US President at the US Capitol in Washington, DC. AFP -
Former President Barack Obama and his wife Michelle arrive for the 59th Presidential Inauguration at the US Capitol for President-elect Joe Biden. AP Photo -
Former US President Bill Clinton arrives with former Secretary of State Hillary Clinton to the inauguration of US President-elect Joe Biden on the West Front of the US Capitol. AFP -
Former US President George W. Bush and his wife Laura Bush arrive for the inauguration of Joe Biden as the 46th President of the United States on the West Front of the US Capitol. Reuters -
Family members of Vice President-elect Kamala Harris attend the inauguration of US President-elect Joe Biden on the West Front of the US Capitol. AFP -
The view from the podium where Joe Biden will speak after being sworn-in during the 59th Presidential Inauguration at the US Capitol in Washington, DC. EPA -
Flags decorate the "Field of Flags" at the National Mall near the Washington Monument ahead of the inauguration of US President-elect Joe Biden. AFP -
President-elect Joe Biden and his wife Jill Biden attend a church service before his presidential inauguration at St Matthews Catholic Church in Washington. Reuters -
President-elect Joe Biden, his wife Jill Biden, Vice President-elect Kamala Harris and her husband Doug Emhoff attend a church service before his presidential inauguration at St. Matthews Catholic Church. Reuters -
The West Front of the US Capitol is prepared for the inauguration of US President-elect Joe Biden in Washington, DC. AFP -
US singer Lady Gaga arrives for the inauguration of Joe Biden as US President in Washington, DC. EPA -
Supporters hold American flags as Air Force One, carrying US President Donald Trump, departs during a farewell ceremony at Joint Base Andrews, Maryland. Bloomberg -
President Donald Trump and first lady Melania Trump wave to a crowd as they board Air Force One at Andrews Air Force Base. AP Photo -
President Donald Trump speaks to crowd before boarding Air Force One at Andrews Air Force Base. AP Photo -
The sun rises behind the US Capitol as preparations are made prior to the 59th inaugural ceremony for President-elect Joe Biden and Vice President-elect Kamala Harris on the West Front of the US Capitol in Washington. AFP
Those who previously followed @POTUS will receive a notification that they can now follow the new account.
The move comes only two weeks after Mr Trump was barred from Twitter, which accused the former president of inciting violence before the January 6 storming of the US Capitol building.
The Biden administration will also be taking over the @WhiteHouse, @PressSec and other handles.
All the posts from the previous administration are archived like those of Mr Trump.
This will also occur on other social media platforms including Facebook and YouTube.
Mr Trump’s @POTUS45 account, which has more than 33 million followers, is being archived and preserved in the National Archives.
