All 20 teams are in action in the Premier League over 10 games spread out on Saturday and Sunday.
It is the last time that will be the case for three weeks as FA Cup fixtures next weekend and then an international break disrupt the schedule.
The action starts on Saturday at 4.30pm UAE time as Brighton and Hove Albion look to boost their hopes of relegation at Crystal Palace.
There are five 7pm games, with Tottenham Hotspur's trip to Southampton the pick of them.
Leaders Manchester City host Watford at 9.30pm, with their title rivals Liverpool taking on Burnley at Anfield at 4pm on Sunday.
Chelsea face Wolves at 6.05pm on Sunday, with the last of the action seeing Manchester United face Arsenal at the Emirates Stadium in a match where both sides need the points to maintain their top-four aspirations.
Ahead of this round of fixtures, sports editor Graham Caygill has made his predictions and explained his reasoning in the photo gallery above. To move on to the next photo, click on the arrows, or if using a mobile device, simply swipe.
