The eyes of a genetically modified mosquito glowing red under ultraviolet light. Getty Images/SPL RM
The eyes of a genetically modified mosquito glowing red under ultraviolet light. Getty Images/SPL RM

Bright ideas light up new sector



What if we used trees to light our streets instead of electric lamp posts?

That simple yet profound question was posed at the beginning of an online promotional video, which was recently used to raise funds for the Glowing Plant project. Conceived as a way to boost awareness about the field of synthetic biology, or "syn bio" as geeks of the trade like to call it, the project also aimed to distribute seeds for plants that would be capable of emitting light.

To raise funds for this scheme, researchers behind the project turned to Kickstarter.com, a crowdfunding site that accepts money from interested members of the public. All told, the researchers raised more than US$484,000 by the end of their campaign on June 7, considerably more than their initial $65,000 target but short of the $500,000 "stretch" goal they later set as the campaign grew in popularity.

Through the project, some seeds of glowing plants have now been sold so that backers will be able to spread and grow them whenever, and wherever, they want.

"We are really just looking at this as a stand-alone project now," says Antony Evans, the project manager for Glowing Plant, whose legal entity name is Senstore. "It's clear there's demand for glowing plants, so in the future, we plan to work on bigger plants and, of course, making them brighter."

The field of synthetic biology is growing in different parts of the world. This science involves the use of biotechnology firms that alter genetic code in plants and animals by taking the genetic information from a useful feature in one organism and adding it into another one.

This sector is being tapped to produce cheaper and more efficient biofuels as well as to excrete the precursors of medical drugs. Companies in the biotech field are also developing products used in agriculture, food and industrial production.

Overall, the global biotechnology industry is forecasted to earn US$262 billion in revenue this year, having increased at an annual rate of 11 per cent over the past five years, according to the market research data from IBISWorld.

But some firms, including Glowing Plant, are discovering it is more difficult to find funds than they originally thought.

"There are a few hurdles," says Anna Son, a healthcare industry analyst who covers biotechnology for IBISWorld. "One of them would be raising capital. Before, it was easier, and start-ups especially had better access to venture capital."

Most of the industry's revenue is still generated within the United States and Europe. The main operators are typically based in geographic clusters made up of firms connected to the biotech industry, such as specialised suppliers and associated research institutions that include hospitals and universities.

"This is largely because companies are small, young, reliant on consistent flows of investment capital or are affiliated or spun off from a university," according to the report from IBISWorld.

Yet companies based in the Asia-Pacific region are expected to see major growth over the next five years. And for the first time this year, the UAE was included in the Scientific American Worldview Scorecard, a list that was issued by the Biotechnology Industry Organisation and ranked the Emirates as 40th out of 54 for innovation and potential within the biotech industry.

The subsector that specialises in genetically modified plants - and glowing plants, more specifically - originally sprouted up more than 25 years ago, when scientists created the first radiating tobacco plant.

More recently, though, the idea to create glowing plants for the Kickstarter project came about after Mr Evans and Omri Amirav-Drory, a biochemist who runs a company called Genome Compiler, completed a summer programme together at Singularity University, a non-profit learning institution in Silicon Valley. Their inspiration: fireflies and aquatic luminescence, which is how animals and plants create and reflect light under water.

"We were chatting [over] lunch at the alumni event about making a glowing plant and so we decided to make it happen," says Mr Evans. "It's just such a sci-fi concept, which remarkably is actually possible."

Genome Compiler is an important piece of this puzzle. The company operates a programme that can design DNA sequences and says it can programme living things "the same way that we design computer code".

So how exactly does all of this fit together to create a glowing plant?

First, experts find the genes in fireflies that make them glow. Genome Compiler's software then rejigs the genes so the plant itself can read what the genes are. These genes then get shipped away (by FedEx or a similar service) and put into a liquid known as agrobacteria.

This concoction, in turn, is used to help to transfer the right genes to the plant to make it glow.

The process does sound like sci-fi, as Mr Evans notes, and it is not yet clear how big a business this might become.

Some may assume the complicated science would hinder the venture. But Mr Evans argues that dealing with biology is the "easy part".

"The biggest challenges are addressing the legal and regulatory aspects of the project and managing the public opinion," he says. "Genetically engineered plants are controversial."

Indeed, environmental groups such as ETC Group, an international organisation based in the United States dedicated to "the conservation and sustainable advancement of cultural and ecological diversity and human rights", have raised concerns to organisations within the US, warning about the dangers of the random and uncontrolled release of bioengineered seeds and plants created from synthetic biology techniques.

"To our knowledge, this would be the first ever intentional environmental release of an avowedly 'synthetic biology' organism in the world," the ETC wrote in a letter to Mr Evans last month, asking him to remove his project on Kickstarter.

"As you are no doubt aware, synthetic biology, while well funded industrially, is still an immature and highly experimental field and not ready for field release," ETC's letter added. "Those life forms are alive, viable, reproducing and their behaviour outside the laboratory is at this point impossible to predict. It is for this reason that many of those who have so far addressed the question of how to govern this new and emerging field have erred on the side of caution and recommended against releasing synthetic organisms to the environment at this time."

In response to this concern, Mr Evans sent a letter of his own to ETC. In it, he said his team was using the term synthetic biology in its most general sense.

"The technology we are using is functionally the same as that which has been used in the creation of many other biotechnology products over the last two decades," Mr Evans wrote in a letter that he shared with The National.

"What is different about this project is the way we are funded, through public donations," he added.

"Our primary goal with the project is to inspire and educate the general public regarding the potential benefits of this technology. It is our opinion that this technology should not be the exclusive preserve of large corporations but that the benefits it brings should be available to everyone."

Whatever the outcome, the prospect of avenues of illuminating trees is an enticing one, at least visually.

If you go

The flights

Emirates flies from Dubai to Seattle from Dh5,555 return, including taxes. Portland is a 260 km drive from Seattle and Emirates offers codeshare flights to Portland with its partner Alaska Airlines.

The car

Hertz (www.hertz.ae) offers compact car rental from about $300 per week, including taxes. Emirates Skywards members can earn points on their car hire through Hertz.

Parks and accommodation

For information on Crater Lake National Park, visit www.nps.gov/crla/index.htm . Because of the altitude, large parts of the park are closed in winter due to snow. While the park’s summer season is May 22-October 31, typically, the full loop of the Rim Drive is only possible from late July until the end of October. Entry costs $25 per car for a day. For accommodation, see www.travelcraterlake.com. For information on Umpqua Hot Springs, see www.fs.usda.gov and https://soakoregon.com/umpqua-hot-springs/. For Bend, see https://www.visitbend.com/.

RESULTS - ELITE MEN

1. Henri Schoeman (RSA) 57:03
2. Mario Mola (ESP) 57:09
3. Vincent Luis (FRA) 57:25
4. Leo Bergere (FRA)57:34
5. Jacob Birtwhistle (AUS) 57:40    
6. Joao Silva (POR) 57:45   
7. Jonathan Brownlee (GBR) 57:56
8. Adrien Briffod (SUI) 57:57           
9. Gustav Iden (NOR) 57:58            
10. Richard Murray (RSA) 57:59       

UAE currency: the story behind the money in your pockets
Famous left-handers

- Marie Curie

- Jimi Hendrix

- Leonardo Di Vinci

- David Bowie

- Paul McCartney

- Albert Einstein

- Jack the Ripper

- Barack Obama

- Helen Keller

- Joan of Arc

Tailors and retailers miss out on back-to-school rush

Tailors and retailers across the city said it was an ominous start to what is usually a busy season for sales.
With many parents opting to continue home learning for their children, the usual rush to buy school uniforms was muted this year.
“So far we have taken about 70 to 80 orders for items like shirts and trousers,” said Vikram Attrai, manager at Stallion Bespoke Tailors in Dubai.
“Last year in the same period we had about 200 orders and lots of demand.
“We custom fit uniform pieces and use materials such as cotton, wool and cashmere.
“Depending on size, a white shirt with logo is priced at about Dh100 to Dh150 and shorts, trousers, skirts and dresses cost between Dh150 to Dh250 a piece.”

A spokesman for Threads, a uniform shop based in Times Square Centre Dubai, said customer footfall had slowed down dramatically over the past few months.

“Now parents have the option to keep children doing online learning they don’t need uniforms so it has quietened down.”

UAE currency: the story behind the money in your pockets
The specs

Price, base / as tested Dh960,000
Engine 3.9L twin-turbo V8
Transmission Seven-speed dual-clutch automatic
Power 661hp @8,000rpm
Torque 760Nm @ 3,000rpm
Fuel economy, combined 11.4L / 100k

Tributes from the UAE's personal finance community

• Sebastien Aguilar, who heads SimplyFI.org, a non-profit community where people learn to invest Bogleheads’ style

“It is thanks to Jack Bogle’s work that this community exists and thanks to his work that many investors now get the full benefits of long term, buy and hold stock market investing.

Compared to the industry, investing using the common sense approach of a Boglehead saves a lot in costs and guarantees higher returns than the average actively managed fund over the long term. 

From a personal perspective, learning how to invest using Bogle’s approach was a turning point in my life. I quickly realised there was no point chasing returns and paying expensive advisers or platforms. Once money is taken care off, you can work on what truly matters, such as family, relationships or other projects. I owe Jack Bogle for that.”

• Sam Instone, director of financial advisory firm AES International

"Thought to have saved investors over a trillion dollars, Jack Bogle’s ideas truly changed the way the world invests. Shaped by his own personal experiences, his philosophy and basic rules for investors challenged the status quo of a self-interested global industry and eventually prevailed.  Loathed by many big companies and commission-driven salespeople, he has transformed the way well-informed investors and professional advisers make decisions."

• Demos Kyprianou, a board member of SimplyFI.org

"Jack Bogle for me was a rebel, a revolutionary who changed the industry and gave the little guy like me, a chance. He was also a mentor who inspired me to take the leap and take control of my own finances."

• Steve Cronin, founder of DeadSimpleSaving.com

"Obsessed with reducing fees, Jack Bogle structured Vanguard to be owned by its clients – that way the priority would be fee minimisation for clients rather than profit maximisation for the company.

His real gift to us has been the ability to invest in the stock market (buy and hold for the long term) rather than be forced to speculate (try to make profits in the shorter term) or even worse have others speculate on our behalf.

Bogle has given countless investors the ability to get on with their life while growing their wealth in the background as fast as possible. The Financial Independence movement would barely exist without this."

• Zach Holz, who blogs about financial independence at The Happiest Teacher

"Jack Bogle was one of the greatest forces for wealth democratisation the world has ever seen.  He allowed people a way to be free from the parasitical "financial advisers" whose only real concern are the fat fees they get from selling you over-complicated "products" that have caused millions of people all around the world real harm.”

• Tuan Phan, a board member of SimplyFI.org

"In an industry that’s synonymous with greed, Jack Bogle was a lone wolf, swimming against the tide. When others were incentivised to enrich themselves, he stood by the ‘fiduciary’ standard – something that is badly needed in the financial industry of the UAE."

Illegal shipments intercepted in Gulf region

The Royal Navy raid is the latest in a series of successful interceptions of drugs and arms in the Gulf

May 11: US coastguard recovers $80 million heroin haul from fishing vessel in Gulf of Oman

May 8: US coastguard vessel USCGC Glen Harris seizes heroin and meth worth more than $30 million from a fishing boat

March 2: Anti-tank guided missiles and missile components seized by HMS Lancaster from a small boat travelling from Iran

October 9, 2022: Royal Navy frigate HMS Montrose recovers drugs worth $17.8 million from a dhow in Arabian Sea

September 27, 2022: US Naval Forces Central Command reports a find of 2.4 tonnes of heroin on board fishing boat in Gulf of Oman 

Switching sides

Mahika Gaur is the latest Dubai-raised athlete to attain top honours with another country.

Velimir Stjepanovic (Serbia, swimming)
Born in Abu Dhabi and raised in Dubai, he finished sixth in the final of the 2012 Olympic Games in London in the 200m butterfly final.

Jonny Macdonald (Scotland, rugby union)
Brought up in Abu Dhabi and represented the region in international rugby. When the Arabian Gulf team was broken up into its constituent nations, he opted to play for Scotland instead, and went to the Hong Kong Sevens.

Sophie Shams (England, rugby union)
The daughter of an English mother and Emirati father, Shams excelled at rugby in Dubai, then after attending university in the UK played for England at sevens.