National League West leaders the Los Angeles Dodgers continued to lead the way in this season's MLB, with a 39th win of the campaign against the Seattle Mariners.
Andre Ethier was their game-changer on this occasion, making light of a 17-match homer drought to blast a grand slam in the second inning.
The New York Yankees completed a morale-boosting series sweep over city rivals the Mets, sealing a 5-4 win.
Russell Martin was key to the success, getting his side on the scoreboard with a two-run hit in the seventh and then following up with the walk-off winner.
National East leaders the Washington Nationals swept the Boston Red Sox with a 4-3 triumph - Roger Bernadina nudging his side ahead with an RBI in the top of the ninth.
American League West front-runners the Texas Rangers zipped the San Francisco Giants 5-0.
Alexi Ogando pitched three no-hit frames before retiring with a groin injury and three relievers picked up where he left off to keep the Giants off the board.
The Tampa Bay Rays defeated the Miami Marlins 4-2 to remain top of American East and extend their winning run in the fixture to seven matches.
The Houston Astros offence had their best day of the season so far, with four homers on 11 hits in an 11-9 victory over the Chicago White Sox.
Four men hit two runs apiece as Sox starter Philip Humber had a torrid day that cost six runs in 5 1/3 innings.
The Detroit Tigers turned a 6-3 deficit into a 7-6 win as they milked misfiring closer Arnoldis Chapman for four runs in the eighth inning.
The Atlanta Braves also saw a lead disappear in dramatic fashion, going 4-0 ahead after three innings only to conceded a dozen unanswered runs to go down 12-4.
Colby Rasmus and Brett Lawrie each collected three RBIs.
The pitchers endured a tough day as Los Angeles Angels bested the Colorado Rockies 10-8.
There was a combined total of five home-runs and 28 hits in the match, with Mark Trumbo the star attraction with a pair of three-run homers.
Andrew McCutchen scored all three runs - including a two-run homer in the third - as the Pittsburgh Pirates edged the Kansas City Royals 3-2, while Ryan Dempster toss eight blank frames in the Chicago Cubs' 8-2 victory over the Minnesota Twins.
Jason Kipnis hit a three-run homer in the top of the ninth to break a 1-1 deadlock and seal a 4-1 victory for the Cleveland Indians over the St Louis Cardinals.
The Baltimore Orioles had Matt Wieters' walk-off double to thank for their 10th-inning 5-4 win against the Philadelphia Phillies, the Arizona Diamondbacks edged the Oakland Athletics 4-3 and the Milwaukee Brewers survived a three-run ninth from the San Diego Padres to edge a 6-5 success.
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