Kevin de Bruyne has been ruled out of Manchester City's clash with Aston Villa on Wednesday as the Premier League leaders wait to discover the full extent of his foot and ankle injury.
The Belgium playmaker was substituted in the second half of his side's FA Cup semi-final defeat to Chelsea.
On Monday, City said they will continue to assess De Bruyne, but did not put a timeline on his recovery.
In a short statement, the club said: "Manchester City can confirm that Kevin de Bruyne suffered injury to his right foot and ankle in Saturday's FA Cup semi-final against Chelsea.
"The extent of the problem is not yet known. Kevin will continue to be reviewed but will miss Wednesday's Premier League trip to Aston Villa. We will bring you further updates on his condition in due course."
Despite losing to Chelsea, Pep Guardiola's side are still fighting on three fronts.
They hold an eight-point lead over Manchester United in the league and face Tottenham in the final of the League Cup at Wembley on Sunday before the first leg of their Champions League semi-final against Paris Saint-Germain next week.
De Bruyne, 29, has scored eight times in his 32 appearances for City this season.
Chelsea v Manchester City ratings
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CHELSEA RATINGS: Kepa Arrizabalaga – 7. Might have been nervy on his return to the side, so would have been grateful to have mainly powder puff shots from distance to field. Reuters -
Cesar Azpilicueta – 5. His cheap giveaway allowed a City break early on, and he got lucky later, too, with a miss-kick in his own box. Got away with a soft header straight after. Reuters -
Thiago Silva – 7. His positioning was so good he barely broke sweat, and he had his Brazilian compatriot Jesus in his pocket throughout. EPA -
Antonio Rudiger – 8. More frenetic and all-action than his centre-half partner Silva, but just as effective. Made crucial interceptions in stoppage time. Reuters -
Reece James – 7. Picked out the other wing back Chilwell with a fine cross from which Chelsea should have led. Cautioned for a foul on Fernandinho. EPA -
Jorginho – 8. Controlled the tempo as Chelsea had the better of the first half, and played a key role in setting up the goal. Reuters -
N'Golo Kante – 7. City’s celebrated midfield found a Kante-shaped roadblock in their way whenever they tried to advance through the middle of the field. AFP -
Ben Chilwell – 7. Skewed a volley wide when well placed from a James cross, but was diligent in defence when he was needed. AFP -
Hakim Ziyech – 8. Had an early goal ruled out after Werner was offside in the build up, but opened the scoring in almost identical circumstances in the second half. AFP -
Timo Werner – 7. Lacked conviction when bearing on goal, and loose in possession at times, but he did provide the assist for Ziyech. AP -
Mason Mount – 6. His face appeared to be grazed slightly by a boot from Fernandinho in an early contretemps. It briefly sparked him, but he was flagging by the second half. Getty -
SUBSTITUTES: Christian Pulisic – 7. Had the ball in the net in injury time after a sharp finish, only for it to be chalked off for offside. Getty -
Kurt Zouma – NA. Manned the battlements for the final few moments after coming on for Silva, who went off with a back injury. Kai Havertz – NA. On for his compatriot Werner late in the second half, and had no time to shine. AFP -
MANCHESTER CITY RATINGS: Zack Steffen – 5. Caught in no-man’s land to present an open goal for Ziyech to score. Made a block on the same player shortly after. AP -
Joao Cancelo – 6. Played a neat reverse pass for Foden to cross as City hinted at finding their swagger at the start of the second phase, but his positive contributions were few otherwise. AFP -
Ruben Dias – 5. Lost his bearings a couple of times to allow Ziyech to ghost into space, and was generally under par throughout. Header over when well placed to score. PA -
Aymeric Laporte – 6. Slid in to block off Werner just after the half-hour mark. Booked in injury time for a foul on Azpilicueta. EPA -
Benjamin Mendy – 5. Untroubled in defence, but could not provide the attacking thrust City needed as they chased the game. Getty -
Rodrigo – 6. Pinched a pass from Azpilicueta to set up a rare early break for City, but otherwise was getting the run around as Chelsea started well. PA -
Fernandinho – 7. Twice escaped censure for recklessness against Mount, against a side he has twice been sent off against before. Tried to rally his side in the second half. PA -
Kevin de Bruyne – 6. Jarred his ankle when vying for the ball with Kante, and was quickly withdrawn. Worrying, given City’s schedule coming up. AP -
Ferran Torres – 6. Looked disconsolate when he was taken off and replaced by Gundogan, but his influence had been minimal. AP -
Raheem Sterling – 4. Too often he was loose and imprecise when his side needed better. His side need him back to his best ASAP, given what follows. AFP -
Gabriel Jesus – 5. No change out of his Brazil colleague Silva, and typified City’s lukewarm effort. Getty -
SUBSTITUTES: Phil Foden – 8. On for the injured De Bruyne early in the second half, and looked a class apart from everyone else in sky blue. AFP -
Ilkay Gundogan – 7. Added some impetus once he was introduced in the second half, but could not do enough to get City back into it. Getty
