Ole Gunnar Solskjaer confirmed Paul Pogba will not play again this month, with Donny Van De Beek and Edinson Cavani also out of Manchester United's Europa League match against Real Sociedad.
The Red Devils were heading to Turin rather than San Sebastian for Thursday's last-32 first leg, with Juventus' Allianz Stadium hosting the match due to the impact of Covid-19 travel restrictions.
Bruno Fernandes, Mason Greenwood and Juan Mata were among the United stars pictured in branded face-masks and neck support cushions as they travelled to Turin by plane.
Pogba will not be stepping out on his old stomping ground due to a thigh issue, while summer signings Van De Beek and Cavani will not be available due to muscle injuries of their own.
"He's recovering well, he's starting the treatment," United boss Solskjaer said of Pogba.
"It'll still be a good few weeks, so he won't be playing in February, that's for sure. Still a few weeks until we see Paul, definitely."
"Apart from that, we have a couple of doubts or doubtful ones if they'll be fit enough in Anthony (Martial) and Scott (McTominay) so we'll have to check them," Solskjaer added.
"And Donny and Edinson definitely not travelling. They are injured, unfortunately. Muscle injuries."
Martial approaches the match having received more sickening racist abuse on social media after United's 1-1 draw at West Brom on Sunday.
"I've spoken to him this morning," Solskjaer said. "He's mentally strong.
"Of course it's not something anyone should have to go through but he definitely seems like he's.. he's not checking all the Instagram or whatever it is, the social media, but it's disgusting.
"We've been talking about this every press conference the last three, four weeks every time now. It used to be sporadic before so there's something we have to do about it."
Solskjaer took a 22-man squad to Italy for the first leg against Sociedad, with 18-year-old Amad Diallo included.
