The 2021/22 Premier League season kicks off on Friday with promoted Brentford hosting Arsenal.
The Bees will be making their Premier League bow and are the 50th club to play in the top tier now in its 30th season.
Manchester City begin their title defence away to Tottenham Hotspur on Sunday while European champions Chelsea take on London rivals Crystal Palace.
Manchester United welcome Leeds United to Old Trafford, Community Shield winners Leicester City face Wolves, Aston Villa are away to new boys Watford and Southampton travel to Everton.
Burnley v Brighton and Newcastle United v West Ham United complete Matchday 1.
Our writers have compiled their predictions for what's in store this campaign.
Andy Mitten - European Football Correspondent
Champions: Manchester City
Top four: Manchester City, Manchester United, Chelsea, Liverpool
Relegated: Watford, Crystal Palace, Norwich City
Top scorer: Edinson Cavani
Surprise package: Brentford
Player of the season: Kevin de Bruyne
Steve Luckings - Deputy Sports Editor
Champions: Manchester City
Top four: Manchester City, Chelsea, Manchester United, Liverpool
Relegated: Brentford, Norwich City, Watford
Top scorer: Romelu Lukaku
Surprise package: Bryan Gil
Player of the season: Jack Grealish
Richard Jolly - Premier League Correspondent
Champions: Manchester City
Top four: Manchester City, Chelsea, Liverpool, Manchester United
Relegated: Brentford, Southampton, Norwich
Top scorer: Mohamed Salah
Surprise package: A Grealish-free Aston Villa
Player of the season: Kevin de Bruyne
Dominic Hart - Sports Editor
Champions: Chelsea
Top four: Chelsea, Manchester City, Manchester United, Liverpool
Relegated: Crystal Palace, Brentford, Newcastle United
Top scorer: Romelu Lukaku
Surprise package: Watford
Player of the season: Romelu Lukaku
Ian Hawkey - European Football Correspondent
Champions: Manchester City
Top four: Manchester City, Chelsea, Manchester United, Liverpool
Relegated: Brentford, Newcastle United, Norwich City
Top scorer: Romelu Lukaku
Surprise package: Bryan Gil
Player of the season: Bruno Fernandes
Gareth Cox - Assistant Sports Editor
Champions: Manchester United
Top four: Manchester United, Manchester City, Chelsea, Liverpool
Relegated: Burnley, Brentford and Norwich
Top scorer: Mohamed Salah
Surprise package: Ivan Toney
Player of the season: Jadon Sancho
Paul Radley - Sports Reporter
Champions: Manchester City
Top four: Manchester City, Chelsea, Manchester United, Liverpool
Relegated: Burnley, Norwich City, Brentford
Top scorer: Romelu Lukaku
Surprise package: Dane Scarlett
Player of the season: Kevin de Bruyne
Jon Turner - Assistant Sports Editor
Champions: Manchester City
Top four: Manchester City, Chelsea, Manchester United, Liverpool
Relegated: Norwich, Watford, Crystal Palace
Top scorer: Mohamed Salah
Surprise package: Newcastle United
Player of the season: Kevin de Bruyne
John McAuley - Sports Reporter
Champions: Manchester City
Top four: Manchester City, Chelsea, Liverpool, Manchester United
Relegated: Norwich, Watford, Brentford
Top scorer: Harry Kane
Surprise package: Michael Olise
Player of the season: Harry Kane