Israel forces attacked Syrian military positions near the Golan Heights frontier in the early hours of Thursday, causing limited damage, Syrian state media said.
The Israeli military claimed it hit three targets in retaliation for an incursion, on Wednesday, of a Syrian drone which was shot down over the north of the country.
"The [Israeli military] holds the Syrian regime accountable for the actions carried out in its territory and warns it from further action against Israeli forces," it said.
Black-and-white surveillance footage released by Israel purportedly shows missiles hitting what appears to be a hut, a two-storey structure and a five-storey structure amid hilly terrain.
Syrian state media said the positions targeted on Thursday were near Hader village in Quneitra province, near the Israeli-occupied Golan Heights.
"The aircraft of the Israeli enemy fired several missiles in the direction of some army positions," state media cited a Syrian military source as saying. At least some of the missiles were thwarted by Syrian air defences, they said.
Israel has grown deeply alarmed by the expanding clout of its arch enemy Iran during the seven-year war in Syria. Its air force has struck scores of targets it describes as Iranian postions or arms transfers to Lebanon's Iran-backed Hezbollah.
Israeli Prime Minister Benjamin Netanyahu told Russia on Wednesday that Israel would not seek to topple Syrian President Bashar Al Assad but that Moscow, Syria's key ally, should encourage Iranian forces to leave Syria, a senior Israeli official said.
Israel has been on high alert as Syrian government forces advance on rebels in the vicinity of the Golan, which Israel took from Syria in the 1967 war. Israel worries Mr Al Assad could let his Iranian allies entrench near its lines or that Syrian forces may defy a 1974 Golan demilitarisation.
Earlier this week, state media said air defence systems struck an Israeli warplane and shot down Israeli missiles targeting the T4 air base in Homs province. Israel neither confirmed nor denied carrying out that strike.
With the help of heavy Russian air power, the Syrian army has seized swathes of Deraa province from insurgents in the south in the past three weeks. The offensive is expected to turn next to rebel parts of Quneitra closer to the Golan.