Newcastle United 0 Tottenham Hotspur 2
Tottenham (Alli 61'), Davies (70')
Red card Jonjo Shelvey (Newcastle)
Captain Jonjo Shelvey was sent off for standing on Dele Alli as Newcastle United's return to the Premier League was ruined by Tottenham Hotspur.
Second-half goals from Alli and Ben Davies ultimately did for the promoted Newcastle with the visitors coasting to a 2-0 victory, but it was Shelvey's 49th-minute dismissal which opened the door after his side had scrapped their way to the break without major incident.
The 25-year-old midfielder, who was banned for five games last season after being accused of making racist comments towards Wolverhamton Wanderers midfielder Romain Saiss, saw red to the astonishment of his teammates and the locals among a crowd of 52,077, although television replays suggested he had stood on Alli's ankle as the Tottenham man lay on the floor.
His impending suspension and injuries to defenders Paul Dummett and Florian Lejeune made it a bad afternoon for manager Rafael Benitez and watching owner Mike Ashley.
In contrast, Spurs manager Mauricio Pochettino left Tyneside having seen a satisfactory performance from his men, who were eventually rewarded for their patience.
Having denied Harry Kane with a point-blank save there was nothing the Republic of Ireland international goalkeeper Rob Elliott could do to keep his side level nine minutes later when Christian Eriksen picked out Alli's run into the box and the England midfielder guided the ball home.
Newcastle's hopes of a comeback were dashed with 20 minutes remaining when the ball broke to full-back Davies inside the penalty area and he slotted past the advancing Elliot, while Kane hit a post in stoppage time to spare them further punishment.
Manchester United 4 West Ham United 0
Man United Lukaku (33', 52'), Martial (87'), Pogba (90')
Romelu Lukaku immediately started to pay off his transfer fee with two goals as Manchester United beat West Ham 4-0 in their Premier League opener.
The £75 million (Dh356m) summer signing struck in each half as United justified pre-season optimism with a sparkling and confident display at Old Trafford.
West Ham were completely outplayed and could easily have trailed by more goals before substitute Anthony Martial and Paul Pogba finally put a more realistic slant on the scoreline in the closing minutes.
You can read Richard Jolly's match report from Old Trafford here.
Manchester City 2 Brighton & Hove Albion 0
Man City Aguero (70'), Dunk (75' og)
Sergio Aguero was on target as Manchester City denied Brighton & Hove Albion any hope of a shock on their Premier League debut.
Pep Guardiola's side, for all their riches, took time to get into their groove in a 2-0 win at the Amex Stadium.
But the moment they did it was ruthless as striker Aguero converted 20 minutes from time.
Lewis Dunk turned Fernandinho's cross through goalkeeper Mathew Ryan grasp and into his own net soon afterwards as City prevailed after previously being frustrated.
City, as expected, dominated possession and hemmed Brighton into their own half.
Yet it took until the 17th minute for the visitors' first strike on goal, when Kevin de Bruyne's free kick was hit straight at Ryan, Albion's new goalkeeper.
City had the ball in Brighton's net after 27 minutes, but it was disallowed.
Gabriel Jesus bundled in following David Silva's lofted pass, but replays showed the ball went in off his right hand. Jesus was booked as he received treatment following a clash with Ryan.
Chelsea 2 Burnley 3
Chelsea Morata (69'), Luiz (88')
Burnley Vokes (24', 43'), Ward (39')
Red cards Cahill, Fabregas (Chelsea)
Chelsea made a dismal start to their Premier League title defence as they fell to a 3-2 defeat by Burnley that featured red cards for Gary Cahill and Cesc Fabregas.
Cahill was sent off by referee Craig Pawson after only 14 minutes when he ended Steven Defour's run with a high tackle that was clumsy rather malicious.
Even when a man down Antonio Conte could not have predicted the capitulation that followed as Burnley stormed 3-0 ahead through two goals from Sam Vokes and a terrific strike by Stephen Ward.
Assisted by a woeful home defence, the underdogs were out of sight by half-time and although Chelsea dominated the second-half with striker Alvaro Morata on target, they had left themselves too much ground to claw back.
Fabregas was given his marching orders after receiving two yellow cards but, despite being reduced to nine men, the champions added a second through David Luiz that at least highlighted a level of desire that was missing before the break.
Burnley hit the post with a free-kick and the match ended with yet another surge from Chelsea who had run out of time to complete their fightback.
Everton 1 Stoke City 0
Everton (Rooney 45+1')
Wayne Rooney's first goal back in blue inspired boyhood club Everton to a narrow opening-weekend victory against Stoke.
After 13 record-breaking years at Manchester United, the 31-year-old England international made the ideal mark on his Premier League homecoming.
Rooney's header late in the first half - his first competitive goal for the club in 4,869 days - broke the deadlock and set Ronald Koeman's Everton on course for a 1-0 win against Stoke at Goodison Park.
Both sides made a tentative start as they deployed three-man defences, with forward Mame Biram Diouf playing as a remodelled right wing-back for the Potters.
The first moment of fluidity of the first half bought a dream stoppage-time opener.
Neat play in the middle saw the ball played wide to Calvert-Lewin. Rooney followed up his involvement in the move by running into the box, breaking free and heading the right-wing cross home to get the Goodison faithful on their feet.
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Crystal Palace 0 Huddersfield Town 3
Huddersfield Ward (23' og), Mounie (26', 78')
Huddersfield made a dream start to their first ever Premier League season with a convincing 3-0 victory over Crystal Palace at Selhurst Park.
Widely dismissed as contenders for relegation before they had even kicked a ball, they produced a typically-energetic display to outclass their experienced hosts, earn three vital points and climb to first place.
Their season may yet descend into a battle for survival, but after Joel Ward's own goal, two fine finishes from club-record signing Steve Mounie gave David Wagner and his team significant reason to believe they may yet be capable of more.
After an unremarkable opening period, it was the visitors who first began to threaten. From Aaron Mooy's 23rd-minute corner, Christopher Schindler flicked on possession towards Mathias Jorgensen, whose unconvincing cross was then poorly turned in by Ward beyond Wayne Hennessey to give Huddersfield the lead.
The hosts' confidence suffered, and it took only a further three minutes for them to concede a second.
With time and space on the left wing, Mooy sent an accurate cross into Palace's area from where Mounie was left unchallenged to routinely head his first goal for the club.
When Scott Dann wasted another chance by shooting over the crossbar, even a draw appeared beyond Palace, but there was still time for Mounie, 22, to score his team's third.
In the 79th minute, substitute Collin Quaner broke and squared to the striker on the edge of the area, from where he classily finished inside the right post to further reward a fine debut display.
Southampton 0 Swansea City 0
Southampton's goal drought at St Mary's stretched to 545 minutes as they laboured to a frustrating Premier League stalemate against Swansea.
The hosts wasted a host of chances to open their new campaign with a galling 0-0 draw against the insipid and limited visitors.
Mauricio Pellegrino's side dominated virtually from start to finish, but lacked the killer instinct needed to clinch the three points.
Southampton have still not scored at home since the 3-1 league win over Crystal Palace on April 5. So despite a new manager, a fresh influx of players and a new season, this was the same profligate Southampton.
Nathan Redmond and Ryan Bertrand combined to lay on scores of openings for their teammates, but James Ward-Prowse, Manolo Gabbiadini and Dusan Tadic were all found wanting in front of goal.
Frenchman Claude Puel paid with his job in the summer for Southampton's inability to link midfield and attack and convert chances last term.
New manager Pellegrino already appears to have generated more impetus than Puel managed, but the south-coast side were still left to rue opportunities missed.
West Bromwich Albion v Bournemouth
WBA Hegazi (31')
Tony Pulis celebrated signing an extended contract in the best possible fashion as West Brom began the new Premier League campaign with a 1-0 win over Bournemouth at The Hawthorns.
Pulis, who will now remain as Baggies manager until 2019 after putting pen to paper on a new deal on Friday, saw new signing Ahmed Hegazi head the only goal of the game in what was an impressive introduction to English football for the central defender.
Another summer arrival, Jay Rodriguez, also made a strong first impression on his debut, particularly early on. The summer signing from Southampton, beset by injury issues in recent seasons, looked fit and mobile and had a handful of attempts inside the first 25 minutes.
Despite their dominance, the hosts looked a little vulnerable to the counter attack and the pace of Josh King and Benik Afobe almost caught them out on a couple of occasions.
West Brom deservedly took the lead after 31 minutes. Rodriguez had looked the most likely to open the scoring but it was another debutant who did so.
After King fouled Allan Nyom out on the right, Chris Brunt delivered a free-kick to the far post and Hegazi's downward header from three yards out found the net.