No stopping Manchester City, Chelsea chop down Manchester United: Premier League predictions

We pick out the winners and losers from the latest round of fixtures

SATURDAY - Manchester City v West Ham (4.30pm): There's just no stopping the Manchester City juggernaught as it hurtles towards the Premier League title. Their winning run is now up to 19 and they sit 10 points clear at the top of the table. West Ham find themselves in the heady heights of fourth but their own unbeaten four-match run is set to end here. Prediction: City 2 West Ham 0. Reuters

West Bromwich Albion v Brighton (7pm): Time is fast running out for second bottom Baggies. They sit 11 points shy of safety and anything less than a win against 16th placed Brighton will be another nail in the relegation coffin for Sam Allardyce's men. Prediction: West Brom 1 Brighton 1. Reuters

Leeds United v Aston Villa (9.30pm): Leeds' rollercoaster season continues to test fans' stomachs. With 11 wins and 12 defeats out of 25 games so far this season, it seems a calm and relaxing draw is usually out of the question for Marco Bielsa's men. A Villa side lacking Jack Grealish could open the door for victory No 12. Prediction: Leeds 3 Villa 1. AFP

Newcastle United v Wolves (midnight): Alarm bells are ringing out on Tyneside as the Magpies now sit just three points outside the bottom three. With top scorer Callum Wilson out injured, all eyes turn to the unpredictable talent of Allan Saint-Maximin for some attacking impetus. Wolves have finally found some form after securing 10 points from the last 12 available. Prediction: Newcastle 1 Wolves 1. EPA

SUNDAY - Cystal Palace v Fulham (4pm): Hopes are rising at Fulham as the Cottagers find themselves just one win away from dragging themselves out of the bottom three. They now have 17th-placed Newcastle firmly in their sights. Palace edged out Brighton 2-1 in their previous game, courtesy of a last-gasp Christian Benteke winner. Prediction: Palace 1 Fulham 0. Reuters

Leicester City v Arsenal (4pm): After narrowly missing out last season, Leicester are once again dreaming of Champions League football. They sit third, six points clear of fifth place Chelsea. Arsenal are languishing down in 11th, 12 points shy of fourth place, and in dire need of a win streak. Prediction: Leicester 2 Arsenal 1. Reuters

Tottenham v Burnley (6pm): The sight of Gareth Bale skinning defenders after coming on against West Ham last week, must have been a sight for sore eyes for beleaguered Spurs fans. It wasn't enough to prevent a fourth defeat in five games but Jose Mourinho's team are in dire need of some of his attacking flair up against a Burnley side unbeaten in four matches. Prediction: Spurs 2 Burnley 0.

Chelsea v Manchester United (8.30pm): The match of the weekend sees fifth-placed Chelsea face second top United at Stamford Bridge. Six points separate the two clubs with United hoping to inflict the first defeat of Blues manager Thomas Tuchel's reign. Prediction: Chelsea 1 United 0. AFP

Sheffield United v Liverpool (11.15pm): Testing times for Liverpool manager Jurgen Klopp after four defeats on the trot and now another injury blow - this time captain Jordan Henderson. Surely rock-bottom Sheffield United cannot make it a miserable five in a row for the reigning champions? Prediction: Sheffield United 1 Liverpool 3. AP

MONDAY - Everton v Southampton (midnight): Fresh from beating Liverpool at Anfield for the first time since 1999, Everton will fancy their chances against a Southampton side without a win in eight matches. The Toffees are five points off a top-four place with a game in hand. Prediction: Everton 2 Southampton 0. PA

Still no time for a breather as we hurtle into the next round of Premier League fixtures.

On Saturday, runaway leaders Manchester City face in-form West United at the Etihad Arena, while the relegation haunted West Bromwich Albion host Brighton. Entertainers Leeds United take on Aston Villa before nervous Newcastle United face Wolves at St James' Park.

Sunday sees Crystal Palace take on Fulham in a London derby at Craven Cottage, high-flying Leicester clash with Arsenal at the King Power Stadium, while Spurs are at home to Burnley. Chelsea meet Manchester Unitted in the match of the weekend and Liverpool bid to end their miserable run when they travel to bottom club Sheffield United. Everton against Southampton completes the fixture list on Monday night.

Predictions for the games are in the photo gallery above. To move on to the next photo, click on the arrows, or if using a mobile device simply