All eyes will be on a blockbusting battle between two of English football's most bitter rivals that takes place on Sunday.
Manchester United, who have just taken over the Premier League top spot from Liverpool after beating Burnley on Tuesday, travel to Merseyside to take on the reigning champions at Anfield.
Paul Pogba, who scored the winner against Burnley, insists the chance to take on Jurgen Klopp's men could not have come at a better time for the in-form Red Devils.
But there is plenty of other action before we get to that clash of the titans. On Thursday night, we have a London derby when Arsenal play host to Crystal Palace.
A hectic Saturday schedule kicks off with a Midlands spat between Wolves and West Bromwich Albion at Molineux, followed by Leeds versus Brighton in Yorkshire. West Ham against Burnley and Fulham versus Chelsea take place in the capital, while Leicester's clash with Southampton at the King Power Stadium completes the day's action.
Sunday starts with Sheffield United versus Tottenham at Bramall Lane, then on to the Liverpool-United game, and finally Manchester City facing Crystal Palace at the Etihad Stadium.
Ahead of the next round of fixtures, check out the predictions in the photo gallery above. To move on to the next photo, click on the arrows or if using a mobile device, simply swipe.
The specs: 2018 Nissan Patrol Nismo
Price: base / as tested: Dh382,000
Engine: 5.6-litre V8
Gearbox: Seven-speed automatic
Power: 428hp @ 5,800rpm
Torque: 560Nm @ 3,600rpm
Fuel economy, combined: 12.7L / 100km
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How it works
Each player begins with one of the great empires of history, from Julius Caesar's Rome to Ramses of Egypt, spread over Europe and the Middle East.
Round by round, the player expands their empire. The more land they have, the more money they can take from their coffers for each go.
As unruled land and soldiers are acquired, players must feed them. When a player comes up against land held by another army, they can choose to battle for supremacy.
A dice-based battle system is used and players can get the edge on their enemy with by deploying a renowned hero on the battlefield.
Players that lose battles and land will find their coffers dwindle and troops go hungry. The end goal? Global domination of course.
Founders: Abdulmajeed Alsukhan, Turki Bin Zarah and Abdulmohsen Albabtain.
Based: Riyadh
Offices: UAE, Vietnam and Germany
Founded: September, 2020
Number of employees: 70
Sector: FinTech, online payment solutions
Funding to date: $116m in two funding rounds
Investors: Checkout.com, Impact46, Vision Ventures, Wealth Well, Seedra, Khwarizmi, Hala Ventures, Nama Ventures and family offices
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GIANT REVIEW
Starring: Amir El-Masry, Pierce Brosnan
Director: Athale
Rating: 4/5
Vidaamuyarchi
Director: Magizh Thirumeni
Stars: Ajith Kumar, Arjun Sarja, Trisha Krishnan, Regina Cassandra
Rating: 4/5