Scott Parker insisted Fulham will come out fighting after Adama Traore's last-gasp winner left the Cottagers three points adrift of Premier League safety.
In added time, Traore escaped down the right before firing home to secure his side's first victory since mid-February.
Wolves striker Willian Jose had earlier been denied his first goal since joining on loan when his well-weighted header in first-half stoppage time was ruled out for an offside by Daniel Podence following a VAR review.
On their third opportunity to move out of the bottom three for the first time since December, Fulham again fell short, slumping to their fourth successive defeat.
Parker said: "It's a painful one tonight and you obviously see that at the end of the game with the scenes of this team and how desperate this team are to be successful.
"I asked the team to show fight, to show desire, to leave everything on the pitch tonight and to a man, we did that. It's a cruel side of football sometimes.
"We've got a fighting chance because of what you see at the end of the game, a team and a group of players that are desperate. This is a group of players that feel passionately about being successful this year, and with that spirit and with that desire you've always got a chance."
Player ratings from the match can be seen in the picture gallery above. To view the next image, click on the arrows or swipe if on a mobile device.