According to the United Nations Office on Drugs and Crime, trafficking in amphetamines has increased in the Middle East in recent years. Photo: Dubai Customs
Specially trained K-9 units are often used by border forces to intercept shipments. EPA
Experts believe the amount intercepted accounts for only around a tenth of the total quantity of pills being smuggled out of places like Syria and Jordan. EPA
Dubai Customs thwarted 398 attempts to smuggle drugs into the city in the first three months of this year. Photo: Dubai Customs
Captagon pills on display after being seized in Greece in 2019. EPA
Captagon became synonymous with the Syrian Civil War. AFP
The small, off-white pills have quickly become one of the most widely consumed drugs in the Middle East. EPA
Millions of Captagon pills are seized around the world each year. EPA
Captagon pills on display after a major interception of a shipment in 2009. Nicole Hill / The National
Customs officers say Captagon smugglers prefer to use sea ports rather than airports because of the size of shipping containers, enabling them to conceal larger quantities of drugs. Photo: Dubai Customs
But what is Captagon, who is consuming it and what effects does it have on users?
What is Captagon?
Captagon was first created in 1961 as an alternative to amphetamine and methamphetamine and was used to treat attention deficit hyperactivity disorder and, less commonly, depression.
The drug, however, was never given regulatory approval by the US Food and Drug Administration (FDA) and in 1981 it was declared a controlled substance after the medical community determined that the drug’s addictive properties outweighed its clinical benefits.
By 1986 manufacturing Captagon had been outlawed in almost every country, but illegal production of the drug continued.
Criminal gangs from Bulgaria and Turkey are believed to have helped to introduce Captagon to the Middle East, where production has flourished in territory beyond the control of fragile states such as Syria and Lebanon.
Today, most of the pills being sold as Captagon across the region have little in common with the tablets produced in the 1960s.
Although stamped with the Captagon logo, these counterfeit pills – often white or yellowish brown in colour – are much less likely to contain fenethylline, the chemical first used in the original tablets.
They are instead more often made up of a mix of other amphetamine derivatives that are easier to produce, as well as additives such as caffeine, quinine and paracetamol.
Who is taking it?
Captagon quickly became associated with the civil war in Syria, after reports emerged of fighters on both sides using the drug on the battlefield.
Talk of ISIS fighters being imbued with supernatural powers after dosing up on handfuls of pills were fanned by producers and the fighters themselves, but have largely been discredited by experts.
Analysts often questioned the drug’s influence on the conflict, pointing instead to the Captagon trade being a lucrative revenue stream for the different warring sides in Syria.The main markets for Captagon are in the Gulf, where it is popular as a recreational drug with young people, particularly in Saudi Arabia.
Data on how widespread the use of Captagon is in Saudi Arabia is scarce, but it is known to be popular as a party drug and among students under pressure to perform academically.
In 2015, the secretary general of Saudi Arabia’s National Committee for Narcotics Control said that the majority of the kingdom’s drug addicts were between 12 and 22 years old, with as many as 40 per cent of those addicted to Captagon being in that age group.
What effects does it have on users?
Captagon is a highly addictive amphetamine. It works by stimulating the central nervous system, increasing alertness and concentration and allowing users to stay awake.
It has been compared with drugs such as Adderall, another amphetamine used to treat ADHD in children.
Despite the descriptions of extremist fighters in Syria feeling invincible while on the drug, the effects of Captagon are generally mild, with users reporting feeling mild euphoria, as well as being talkative and more energetic.
But Captagon abuse can have devastating consequences for those who become addicted.
Long-term amphetamine users can suffer from a range of side effects including confusion, hallucinations, nausea, vomiting, seizures, high blood pressure and heart palpitations, according to The Cabin, an addiction services group that operates in Saudi Arabia.
Other side effects reported by regular users include blurred vision, vertigo, breathing difficulties, heart palpitations, gastrointestinal symptoms, muscle and joint pain, mood swings, confusion, feelings of anger and irritability.
When users try to quit taking Captagon pills, they often encounter strong withdrawal symptoms, including fatigue, that cause them to seek out the drug again.
Treatment for Captagon addiction usually includes psychotherapy, as well as exercise and diet programmes.
Who's who in Yemen conflict
Houthis: Iran-backed rebels who occupy Sanaa and run unrecognised government
Yemeni government: Exiled government in Aden led by eight-member Presidential Leadership Council
Southern Transitional Council: Faction in Yemeni government that seeks autonomy for the south
Habrish 'rebels': Tribal-backed forces feuding with STC over control of oil in government territory
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Timeline
2012-2015
The company offers payments/bribes to win key contracts in the Middle East
May 2017
The UK SFO officially opens investigation into Petrofac’s use of agents, corruption, and potential bribery to secure contracts
September 2021
Petrofac pleads guilty to seven counts of failing to prevent bribery under the UK Bribery Act
October 2021
Court fines Petrofac £77 million for bribery. Former executive receives a two-year suspended sentence
December 2024
Petrofac enters into comprehensive restructuring to strengthen the financial position of the group
May 2025
The High Court of England and Wales approves the company’s restructuring plan
July 2025
The Court of Appeal issues a judgment challenging parts of the restructuring plan
August 2025
Petrofac issues a business update to execute the restructuring and confirms it will appeal the Court of Appeal decision
October 2025
Petrofac loses a major TenneT offshore wind contract worth €13 billion. Holding company files for administration in the UK. Petrofac delisted from the London Stock Exchange
Monday, January 28
Iran v Japan, Hazza bin Zayed Stadium (6pm)
Tuesday, January 29
UAEv Qatar, Mohamed Bin Zayed Stadium (6pm)
Friday, February 1
Final, Zayed Sports City Stadium (6pm)
HIV on the rise in the region
A 2019 United Nations special analysis on Aids reveals 37 per cent of new HIV infections in the Mena region are from people injecting drugs.
New HIV infections have also risen by 29 per cent in western Europe and Asia, and by 7 per cent in Latin America, but declined elsewhere.
Egypt has shown the highest increase in recorded cases of HIV since 2010, up by 196 per cent.
Access to HIV testing, treatment and care in the region is well below the global average.
Few statistics have been published on the number of cases in the UAE, although a UNAIDS report said 1.5 per cent of the prison population has the virus.
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