Saudi astronauts Rayyanah Barnawi and Ali Al Qarni have a jam-packed schedule during their eight-day stay on the International Space Station, including science experiments around cancer research.
They are the first Saudi citizens in space since 1985, with the kingdom hoping that their mission inspires young Arabs into science, tech, maths and engineering subjects.
Ms Barnawi, 33, a research scientist, and Mr Al Qarni, 31, a fighter pilot, arrived at the orbiting outpost on Monday.
Their trip also means that researchers across Saudi Arabia had the opportunity to send crucial experiments on health sciences and weather technology with the astronauts, so they could be tested in microgravity conditions.
Mishaal Ashemimry, special adviser to the chief executive of the Saudi Space Commission, spoke to The National on Monday about the astronauts' activities.
“We have 11 scientific experiments and three outreach experiments, so a total of 14,” she said.
“Six of those experiments are focused on human health, and trying to understand the effect of microgravity and a short stay mission on the nervous system on a cellular level, tissue level and on an organ.
“Four experiments are going to be focused on inflammatory responses, which has implications to cancer.
“And then one of the experiments is kind of unique in the fact that it is the first to look at artificial rain or cloud seeding in microgravity.”
Cancer research in space
Ms Barnawi has nearly a decade of experience in cancer stem-cell research and will be using her expertise on the station.
She will be taking part in a study called Modelling Tumour Organoids that could help develop stem cell models that help predict and prevent cancer.
The research involves monitoring breast cancer cells to study immune dysfunction and drug challenges.
It is hoped the experiment will help improve the detection of and therapies for pre-cancer, cancer and a variety of other diseases.
Researchers at the Space Stem Cell Orbital Research programme, in partnership with Sanford Stem Cell Institute, the JM Foundation and Axiom Space, have sent the experiment.
Studying human immune cells
Another life sciences experiment involves investigating the inflammatory response of human immune cells in microgravity.
Ms Barnawi will study the changes in mRNA decay, a process that regulates gene expression changes in cells and can influence the effects of inflammation.
Researchers from the Saudi Arabia's King Faisal Specialist Hospital and Research Centre have sent a type of white blood cells to the ISS that will be treated with a substance that stimulates an inflammatory response.
It will be carried out in parallel with experiments on the ground, to help scientists measure the difference in results.
Findings could help researchers better understand the immune system and develop potential therapies for inflammatory diseases in space and on Earth.
Cloud seeding experiments
Mr Al Qarni will be carrying out a physical science experiment that involves cloud seeding, or artificial rain.
This is the first time cloud seeding will be studied in microgravity conditions.
“The goal of this experiment is to essentially look at the potential to create water droplets by using the same methods for cloud seeding, which is introducing silver iodide into moisture, and to see if it can create nucleation and produce water droplets,” Ms Ashemimry said.
This could help create artificial rain in lower-gravity areas like the Moon and Mars, she said.
Mr Al Qarni will mix moist air and salt crystals in a reaction chamber to see if water droplets form.
The experiment has been sent by the King Fahd University of Petroleum and Minerals, the Saudi Space Commission and Nanoracks, a US company that helps its customers launch experiments and technology to space.
Ten tax points to be aware of in 2026
1. Domestic VAT refund amendments: request your refund within five years
If a business does not apply for the refund on time, they lose their credit.
2. E-invoicing in the UAE
Businesses should continue preparing for the implementation of e-invoicing in the UAE, with 2026 a preparation and transition period ahead of phased mandatory adoption.
3. More tax audits
Tax authorities are increasingly using data already available across multiple filings to identify audit risks.
4. More beneficial VAT and excise tax penalty regime
Tax disputes are expected to become more frequent and more structured, with clearer administrative objection and appeal processes. The UAE has adopted a new penalty regime for VAT and excise disputes, which now mirrors the penalty regime for corporate tax.
5. Greater emphasis on statutory audit
There is a greater need for the accuracy of financial statements. The International Financial Reporting Standards standards need to be strictly adhered to and, as a result, the quality of the audits will need to increase.
6. Further transfer pricing enforcement
Transfer pricing enforcement, which refers to the practice of establishing prices for internal transactions between related entities, is expected to broaden in scope. The UAE will shortly open the possibility to negotiate advance pricing agreements, or essentially rulings for transfer pricing purposes.
7. Limited time periods for audits
Recent amendments also introduce a default five-year limitation period for tax audits and assessments, subject to specific statutory exceptions. While the standard audit and assessment period is five years, this may be extended to up to 15 years in cases involving fraud or tax evasion.
8. Pillar 2 implementation
Many multinational groups will begin to feel the practical effect of the Domestic Minimum Top-Up Tax (DMTT), the UAE's implementation of the OECD’s global minimum tax under Pillar 2. While the rules apply for financial years starting on or after January 1, 2025, it is 2026 that marks the transition to an operational phase.
9. Reduced compliance obligations for imported goods and services
Businesses that apply the reverse-charge mechanism for VAT purposes in the UAE may benefit from reduced compliance obligations.
10. Substance and CbC reporting focus
Tax authorities are expected to continue strengthening the enforcement of economic substance and Country-by-Country (CbC) reporting frameworks. In the UAE, these regimes are increasingly being used as risk-assessment tools, providing tax authorities with a comprehensive view of multinational groups’ global footprints and enabling them to assess whether profits are aligned with real economic activity.
Contributed by Thomas Vanhee and Hend Rashwan, Aurifer
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Benefits of first-time home buyers' scheme
- Priority access to new homes from participating developers
- Discounts on sales price of off-plan units
- Flexible payment plans from developers
- Mortgages with better interest rates, faster approval times and reduced fees
- DLD registration fee can be paid through banks or credit cards at zero interest rates
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The burning issue
The internal combustion engine is facing a watershed moment – major manufacturer Volvo is to stop producing petroleum-powered vehicles by 2021 and countries in Europe, including the UK, have vowed to ban their sale before 2040. The National takes a look at the story of one of the most successful technologies of the last 100 years and how it has impacted life in the UAE.
Read part four: an affection for classic cars lives on
Read part three: the age of the electric vehicle begins
Read part one: how cars came to the UAE
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