Sars-CoV-2 was found in the hearts of most people who died as a result of complications from the virus, a small study has found.
Scientists in the US examined about 1,000 pieces of heart tissue from 41 patients, in what is thought to be the most detailed study of its kind.
The virus, which causes Covid-19, was found to be present in the hearts of 30 of them.
It was only these patients who developed new abnormal heartbeats, which were fast, irregular or included early or extra heartbeats, compared with the other patients.
The surprise was that this respiratory virus makes a beeline for the cells lining blood vessels
Scientists do not know why the virus attacked the hearts of the patients.
"Comorbidities are present in many patients with Covid-19 with critical illness," said the scientists, who carried out the study at Massachusetts General Hospital.
“However, cardiac inflammation was associated with neither the underlying medical conditions nor the composite risk factor scores.”
Instead, it correlated strongly with the duration of symptoms and hospital stay, suggesting heart damage may result in "many patients with a long Covid-19 illness prior to death".
The authors pointed out the research focused on patients with fatal Covid-19 whose bodies underwent postmortem examinations.
They said the results might not be applicable to all patients dying with Covid-19.
“In a study of our hospital’s Sars-CoV-2 testing facility, the median age of all patients testing positive for Sars-CoV-2 during the spring of 2020 was 47, with 50 per cent being men, compared with a median age of 67 and 66 per cent men in our autopsy series.
“Thus, our observations may not be generalisable to all patients with Sars-CoV-2 infection.”
Some doctors have questioned whether Covid-19 is a vascular disease, rather than a respiratory one, due to its ability to cause clots.
In a study published last summer, researchers compared the lung tissues of people who died from complications related to Covid-19 with those who died from influenza.
Surprisingly, they found that lung tissue of Covid-19 patients had nine times as many tiny blood clots as those of the flu patients. In addition, the endothelial tissue in coronavirus-infected lungs exhibited “severe” injury.
“The surprise was that this respiratory virus makes a beeline for the cells lining blood vessels, filling them up like a gumball machine and shredding the cell from the inside out,” Dr William Li, a vascular biologist who led the study, told broadcaster NPR.
“We found blood vessels are blocked and blood clots are forming because of that lining damage.”
Coronavirus in the UAE
Will the pound fall to parity with the dollar?
The idea of pound parity now seems less far-fetched as the risk grows that Britain may split away from the European Union without a deal.
Rupert Harrison, a fund manager at BlackRock, sees the risk of it falling to trade level with the dollar on a no-deal Brexit. The view echoes Morgan Stanley’s recent forecast that the currency can plunge toward $1 (Dh3.67) on such an outcome. That isn’t the majority view yet – a Bloomberg survey this month estimated the pound will slide to $1.10 should the UK exit the bloc without an agreement.
New Prime Minister Boris Johnson has repeatedly said that Britain will leave the EU on the October 31 deadline with or without an agreement, fuelling concern the nation is headed for a disorderly departure and fanning pessimism toward the pound. Sterling has fallen more than 7 per cent in the past three months, the worst performance among major developed-market currencies.
“The pound is at a much lower level now but I still think a no-deal exit would lead to significant volatility and we could be testing parity on a really bad outcome,” said Mr Harrison, who manages more than $10 billion in assets at BlackRock. “We will see this game of chicken continue through August and that’s likely negative for sterling,” he said about the deadlocked Brexit talks.
The pound fell 0.8 per cent to $1.2033 on Friday, its weakest closing level since the 1980s, after a report on the second quarter showed the UK economy shrank for the first time in six years. The data means it is likely the Bank of England will cut interest rates, according to Mizuho Bank.
The BOE said in November that the currency could fall even below $1 in an analysis on possible worst-case Brexit scenarios. Options-based calculations showed around a 6.4 per cent chance of pound-dollar parity in the next one year, markedly higher than 0.2 per cent in early March when prospects of a no-deal outcome were seemingly off the table.
Bloomberg
Ms Yang's top tips for parents new to the UAE
- Join parent networks
- Look beyond school fees
- Keep an open mind
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