The leading scientist behind the AstraZeneca vaccine expects Covid-19 to recede into the same category as other coronaviruses and cause symptoms no worse than a common cold.
Dame Sarah Gilbert was speaking at a webinar hosted by the Royal Society of Medicine on Wednesday and said there was not an enormous amount of concern about future variants of the virus.
The virologist said the spike protein targeted by vaccines was limited in its ability to mutate to avoid immunity that could potentially make vaccines less effective.
“There aren’t very many places for the viruses to go to have something that will evade immunity but still be a really infective virus,” she said.
“I don’t think there’s an enormous amount of concern that we’re suddenly going to see a switch to something that evades existing immunity.
“What tends to happen over time is there’s just a slow drift, that’s what happens with flu viruses.”
For the virus to completely mutate, its spike protein must interact with the receptor on the surface of the human cell so it can get inside.
If the virus changes its spike protein too much it is unable to interact with the cell’s Ace2 receptor, making it impenetrable.
Small changes to the virus over time is a more likely scenario, that will enable virologists and vaccine manufacturers to adapt and react to those changes, similarly to the way the annual flu vaccine is developed.
Earlier this month, Ms Gilbert said the developing world where vaccines are scarce should be the priority of distribution of supplies of injections, rather than booster campaigns.
The Oxford University professor said immunity in those already given the Pfizer and AstraZeneca doses was holding up well.
Vaccinations for flu season begin in Dubai - in pictures
-

Dubai began a vaccination campaign before the flu season. All photos by Nick Webster / The National -

The Ministry of Health and Prevention is encouraging people in vulnerable groups to take the flu vaccine this winter free of charge. -

People obtain flu vaccine shots in Dubai. -

Flu vaccines are recommended for everyone above the age of six months.
How%20to%20avoid%20getting%20scammed
Combating coronavirus
Nick March: coronavirus dark cloud could have a silver lining
Gavin Esler: coronavirus offers a stinging rebuke to protectionists
Rashmee Roshan Lall: we will learn how to be vulnerable together
SPEC%20SHEET%3A%20APPLE%20M3%20MACBOOK%20AIR%20(13%22)
Spider-Man%202
Tamkeen's offering
- Option 1: 70% in year 1, 50% in year 2, 30% in year 3
- Option 2: 50% across three years
- Option 3: 30% across five years
Match info
Uefa Champions League Group B
Tottenham Hotspur 1 (Eriksen 80')
Inter Milan 0
Cricket World Cup League 2
UAE squad
Rahul Chopra (captain), Aayan Afzal Khan, Ali Naseer, Aryansh Sharma, Basil Hameed, Dhruv Parashar, Junaid Siddique, Muhammad Farooq, Muhammad Jawadullah, Muhammad Waseem, Omid Rahman, Rahul Bhatia, Tanish Suri, Vishnu Sukumaran, Vriitya Aravind
Fixtures
Friday, November 1 – Oman v UAE
Sunday, November 3 – UAE v Netherlands
Thursday, November 7 – UAE v Oman
Saturday, November 9 – Netherlands v UAE
• Remittance charges will be tackled by blockchain
• UAE's monumental and risky Mars Mission to inspire future generations, says minister
• Could the UAE drive India's economy?
• News has a bright future and the UAE is at the heart of it
• Architecture is over - here's cybertecture
• The National announces Future of News journalism competition
• Round up: Experts share their visions of the world to come
The%20US%20Congress%2C%20explained
Confirmed%20bouts%20(more%20to%20be%20added)
On Women's Day
Dr Nawal Al-Hosany: Why more women should be on the frontlines of climate action
Shelina Janmohamed: Why shouldn't a spouse be compensated fairly for housework?
Samar Elmnhrawy: How companies in the Middle East can catch up on gender equality
The National Editorial: Is there much to celebrate on International Women's Day 2021?
Anxiety and work stress major factors
Anxiety, work stress and social isolation are all factors in the recogised rise in mental health problems.
A study UAE Ministry of Health researchers published in the summer also cited struggles with weight and illnesses as major contributors.
Its authors analysed a dozen separate UAE studies between 2007 and 2017. Prevalence was often higher in university students, women and in people on low incomes.
One showed 28 per cent of female students at a Dubai university reported symptoms linked to depression. Another in Al Ain found 22.2 per cent of students had depressive symptoms - five times the global average.
It said the country has made strides to address mental health problems but said: “Our review highlights the overall prevalence of depressive symptoms and depression, which may long have been overlooked."
Prof Samir Al Adawi, of the department of behavioural medicine at Sultan Qaboos University in Oman, who was not involved in the study but is a recognised expert in the Gulf, said how mental health is discussed varies significantly between cultures and nationalities.
“The problem we have in the Gulf is the cross-cultural differences and how people articulate emotional distress," said Prof Al Adawi.
“Someone will say that I have physical complaints rather than emotional complaints. This is the major problem with any discussion around depression."
Daniel Bardsley
Courses%20at%20Istituto%20Marangoni%2C%20Dubai
TECH%20SPECS%3A%20APPLE%20WATCH%20SERIES%209
A%20QUIET%20PLACE
Killing of Qassem Suleimani
National Editorial: Suleimani has been killed, now we must de-escalate
Mina Al Oraibi: Air strike casts a long shadow over the decade ahead
Matthew Levitt: Iran retains its ability to launch terror attacks
Damien McElroy: A CEO tasked with spreading Iran's influence
Hussein Ibish: Trump's order on solid constitutional ground
Simon Waldman: Cautious Israel keeping a low profile
Skoda Superb Specs
Engine: 2-litre TSI petrol
Power: 190hp
Torque: 320Nm
Price: From Dh147,000
Available: Now
Florence and the Machine – High as Hope
Three stars
MATCH INFO
Uefa Champions League semi-final, first leg
Tottenham v Ajax, Tuesday, 11pm (UAE).
Second leg
Ajax v Tottenham, Wednesday, May 8, 11pm
Games on BeIN Sports
Voices: How A Great Singer Can Change Your Life
Nick Coleman
Jonathan Cape
Turkish Ladies
Various artists, Sony Music Turkey
While you're here
National Editorial: World trade has started to look inwards
Callum Patton: ‘Arrival of Asian century’ has eclipsed US
Robin Mills: Importance of China's energy markets clearer









