Barcelona midfielder Sergio Busquets left Spain's pre-Euro 2020 training camp on Sunday after testing positive for Covid-19, the country's football federation (RFEF) announced.
Spain captain Busquets, 32, tested positive earlier on Sunday, the RFEF said in a statement, and those who were in close contact with the midfielder "will remain isolated" as a preventative measure.
The rest of the Spain squad all tested negative.
Ahead of Spain's first match against Sweden on June 14, the squad will carry out individual training programmes in the build-up to the Euro, which begins on Friday.
Spain manager Luis Enrique has until Saturday to make changes to his squad ahead of their opening fixture in Seville.
"Appropriate sporting measures will be assessed according to the situation of the national team captain," the RFEF said.
Busquets, capped 123 times for Spain, has won the 2010 World Cup and Euro 2012 with his national team. He has also won eight La Liga titles, seven Copa del Reys and three Champions Leagues with Barcelona.
Busquets' positive test and temporary exit from the Spain squad comes after It comes after the Netherlands dropped goalkeeper Jasper Cillessen from their squad because of a positive test.
"We don't know how long it will take until he is 100 per cent fit again. I don't want to take any risks in that respect," Dutch coach Frank de Boer said.
Company%20Profile
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New Zealand 15 British & Irish Lions 15
New Zealand 15
Tries: Laumape, J Barrett
Conversions: B Barrett
Penalties: B Barrett
British & Irish Lions 15
Penalties: Farrell (4), Daly
KILLING OF QASSEM SULEIMANI
Ain Dubai in numbers
126: The length in metres of the legs supporting the structure
1 football pitch: The length of each permanent spoke is longer than a professional soccer pitch
16 A380 Airbuses: The equivalent weight of the wheel rim.
9,000 tonnes: The amount of steel used to construct the project.
5 tonnes: The weight of each permanent spoke that is holding the wheel rim in place
192: The amount of cable wires used to create the wheel. They measure a distance of 2,4000km in total, the equivalent of the distance between Dubai and Cairo.
COMPANY PROFILE
Name: Akeed
Based: Muscat
Launch year: 2018
Number of employees: 40
Sector: Online food delivery
Funding: Raised $3.2m since inception
Jawan
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TRAP
Starring: Josh Hartnett, Saleka Shyamalan, Ariel Donaghue
Director: M Night Shyamalan
Rating: 3/5