Coach Maurizio Sarri said he was "bitter" as Juventus crashed out of the Champions League against Lyon despite Cristiano Ronaldo's double giving the Italians a 2-1 win on the night.
Captain Memphis Depay's 12th-minute penalty sealed Lyon's place in the quarter-finals with a 2-2 aggregate score to go through on away goals, and they will now face Manchester City at the final tournament in Lisbon.
"I am very bitter, I understand how much this competition is cursed for Juve," said Sarri, who took over as coach last summer.
The Turin side have won the tournament twice, but not since 1996, and have been runners-up seven times, including twice in the last five years.
Sarri's team, who won a ninth consecutive league title in Italy, were up against French opponents who were fresh after Ligue 1 was cancelled five months ago because of coronavirus.
"The regret is to have missed the first half in Lyon. At this level it costs," added Sarri, talking of the first leg played back in February.
"They had a much more logical preparation than ours. I'm going home sad because we are beaten, but tonight we had a good game.
"We were immediately behind with a penalty which for me is crazy, much more than questionable.
"But they gave everything and fought to the end. Juve had a good game and Lyon suffered a lot.
"If I weren't devastated by the elimination, I would be happy with tonight's performance, because we brought out so much energy and the team responded with character and showed that they have recovered in the last few days."
Depay's penalty put Rudi Garcia's side two goals ahead in the tie and left Juve with a mountain to climb.
Needing to score three in order to go through, Ronaldo tried his best to drag the Italian champions over the line.
He levelled the scores on the night with a penalty of his own with two minutes left in the opening period before crashing a second home on the hour mark.
Lyon managed to hold on to set up a clash with Pep Guardiola's City, who put out 13-times winners Real Madrid, on August 15.
Lyon boss Rudi Garcia, said: "We came up against an opponent who has an extraterrestrial in its squad," of five-time Ballon d'Or winner Ronaldo.
"This is the victory of a group. We wanted to be in the final eight in Lisbon, we are there.
"We'll still be outsiders and that suits us very well."