Skull and mandible 236, dating from between 2687 and 2345BC, which belonged to a male aged 30 to 35. Photo: Tondini, Isidro, Camarós
Skull and mandible 236, dating from between 2687 and 2345BC, which belonged to a male aged 30 to 35. Photo: Tondini, Isidro, Camarós
Skull and mandible 236, dating from between 2687 and 2345BC, which belonged to a male aged 30 to 35. Photo: Tondini, Isidro, Camarós
Skull and mandible 236, dating from between 2687 and 2345BC, which belonged to a male aged 30 to 35. Photo: Tondini, Isidro, Camarós

4,000-year-old skulls suggest ancient Egyptians tried to treat cancer with surgery


Gillian Duncan
  • English
  • Arabic

Ancient Egyptians may have tried to treat cancer with surgery, according to a new study that has uncovered the earliest known evidence of a procedure for the disease.

Texts dating back thousands of years describe ancient Egyptians’ advanced knowledge of medicine, including identifying and treating numerous diseases and traumatic injuries, using prostheses and dental fillings.

But it was not believed that they knew how to treat cancer, until now.

Studying ancient skulls, scientists discovered cut marks around cancerous lesions – appearing to provide evidence of experimental treatments or medical explorations of the disease.

Was it a treatment or a postmortem intervention? We cannot tell, but clearly, they were trying to deal with it
Prof Edgard Camaros,
University of Santiago de Compostela

Lead author Prof Edgard Camaros from the University of Santiago de Compostela, in Spain, told The National that the team’s research “changes our understanding of the history of medicine”.

“This is the earliest known, at least for the moment, surgical procedure related to a cancerous tumour,” he said.

“Was it a treatment or a postmortem intervention? We cannot tell, but clearly they were trying to deal with it.”

Researchers made the discovery as part of efforts to understand more about the role of cancer in the past and how prevalent it was in ancient societies.

They studied two Egyptian skulls in the University of Cambridge’s Duckworth Collection. One, from between 2687 and 2345BC, belonged to a male aged 30 to 35. The other, from between 663 and 343BC, belonged to a female who was older than 50 years.

The man’s skull showed evidence of a large lesion consistent with excessive tissue destruction, a condition known as neoplasm. There were also 30 or so small and round metastasised lesions scattered across the skull, with cut marks, which appeared to be from surgery.

Egypt archaeologists unearth 110 ancient tombs in Nile Delta – in pictures

  • This photo provided by the Egyptian Tourism and Antiquities Ministry shows an ancient burial tomb at the Koum El Khulgan archeological site, in the Nile Delta province of Dakahlia. Egypt tourism ministry via AP
    This photo provided by the Egyptian Tourism and Antiquities Ministry shows an ancient burial tomb at the Koum El Khulgan archeological site, in the Nile Delta province of Dakahlia. Egypt tourism ministry via AP
  • Ancient burial tombs unearthed recently, some with human remains, in the Koum El Khulgan archeological site. Egyptian Tourism and Antiquities Ministry via AP
    Ancient burial tombs unearthed recently, some with human remains, in the Koum El Khulgan archeological site. Egyptian Tourism and Antiquities Ministry via AP
  • An ancient burial tomb unearthed recently with human remains, in the Koum El Khulgan archeological site. Egyptian Tourism and Antiquities Ministry via AP
    An ancient burial tomb unearthed recently with human remains, in the Koum El Khulgan archeological site. Egyptian Tourism and Antiquities Ministry via AP
  • An ancient burial tomb unearthed recently with human remains and and pottery, in the Koum El Khulgan archeological site. Egyptian Tourism and Antiquities Ministry via AP
    An ancient burial tomb unearthed recently with human remains and and pottery, in the Koum El Khulgan archeological site. Egyptian Tourism and Antiquities Ministry via AP

“This evidences a surgical intervention directly related to cancerous tumours that show that they were somehow trying to understand oncological conditions,” said Prof Camaros.

“Similar techniques were used (and sometimes still used) related to oncological surgical intervention. However, successful cancer treatment is a milestone of recent modern medicine,” he added.

The second skull, belonging to the woman, had a large lesion consistent with a cancerous tumour that destroyed the bone. The researchers said that may indicate cancer was common in the past.

It also showed two healed lesions from past traumatic injuries, one of which appeared to have been caused by a sharp weapon. The researchers say that may suggest the woman received some kind of treatment and survived as a result. Wounds were uncommon in women, with most violence-related injuries found in males.

“Was this female individual involved in any kind of warfare activities?” said Tatiana Tondini, a researcher at the University of Tubingen and first author of the study, published in Frontiers in Medicine.

“If so, we must rethink the role of women in the past and how they took an active part in conflicts during antiquity.”

According to the Cancer History Project, ancient Egyptians knew and understood cancer.

The first earliest written observation of cancer was found in a papyrus dating from about 3000 to 2500BC. It detailed case studies of several breast tumours, with accounts “astonishingly akin to descriptive data that a modern physician might summarise in their clinical text today”.

Treatments described in the papyrus were, however, very different to modern techniques, including “binding the tumour with fresh meat (potentially for haemostasis) on the first day, followed by application of grease, honey, and lint every day (potentially as an ointment) until the patient recovers”.

“The ancient physicians also used astringent to dry the wounds in the tumour. However, an interesting case is a bulging tumour with swellings spread over the breast and cool to the touch, for which the physician does not prescribe any treatment, possibly because this was an untreatable tumour at that time,” it said.

Ten tax points to be aware of in 2026

1. Domestic VAT refund amendments: request your refund within five years

If a business does not apply for the refund on time, they lose their credit.

2. E-invoicing in the UAE

Businesses should continue preparing for the implementation of e-invoicing in the UAE, with 2026 a preparation and transition period ahead of phased mandatory adoption. 

3. More tax audits

Tax authorities are increasingly using data already available across multiple filings to identify audit risks. 

4. More beneficial VAT and excise tax penalty regime

Tax disputes are expected to become more frequent and more structured, with clearer administrative objection and appeal processes. The UAE has adopted a new penalty regime for VAT and excise disputes, which now mirrors the penalty regime for corporate tax.

5. Greater emphasis on statutory audit

There is a greater need for the accuracy of financial statements. The International Financial Reporting Standards standards need to be strictly adhered to and, as a result, the quality of the audits will need to increase.

6. Further transfer pricing enforcement

Transfer pricing enforcement, which refers to the practice of establishing prices for internal transactions between related entities, is expected to broaden in scope. The UAE will shortly open the possibility to negotiate advance pricing agreements, or essentially rulings for transfer pricing purposes. 

7. Limited time periods for audits

Recent amendments also introduce a default five-year limitation period for tax audits and assessments, subject to specific statutory exceptions. While the standard audit and assessment period is five years, this may be extended to up to 15 years in cases involving fraud or tax evasion. 

8. Pillar 2 implementation 

Many multinational groups will begin to feel the practical effect of the Domestic Minimum Top-Up Tax (DMTT), the UAE's implementation of the OECD’s global minimum tax under Pillar 2. While the rules apply for financial years starting on or after January 1, 2025, it is 2026 that marks the transition to an operational phase.

9. Reduced compliance obligations for imported goods and services

Businesses that apply the reverse-charge mechanism for VAT purposes in the UAE may benefit from reduced compliance obligations. 

10. Substance and CbC reporting focus

Tax authorities are expected to continue strengthening the enforcement of economic substance and Country-by-Country (CbC) reporting frameworks. In the UAE, these regimes are increasingly being used as risk-assessment tools, providing tax authorities with a comprehensive view of multinational groups’ global footprints and enabling them to assess whether profits are aligned with real economic activity. 

Contributed by Thomas Vanhee and Hend Rashwan, Aurifer

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October 4: Round One of Rotax Max Challenge, Al Ain (karting)

October 1: 1 Round One of the inaugural UAE Desert Championship (rally)

November 1-3: Abu Dhabi Grand Prix (Formula One)

November 28-30: Dubai International Rally

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Updated: May 29, 2024, 11:47 AM