Efforts to end the Covid-19 pandemic could be hampered by public fears over the safety of vaccines, according to a new global survey.
Researchers are now calling for action from authorities and experts alike to build public confidence ahead of the roll-out of a potential Covid-19 vaccine.
There are currently six research laboratories in Phase 3 of World Health Organisation-recognised clinical trials for a vaccine.
The scientific and public health community needs to do much better at building public trust in the safety of vaccination
The report found that trust in vaccines is relatively low in Europe - ranging from 19 per cent in Lithuania to 66 per cent in Finland in December 2019 - but is on the rise in other parts of the continent such as France, Italy and the UK.
Significant spikes in numbers disagreeing that vaccines are safe were noted in Azerbaijan (from 2 per cent of those surveyed in 2015 to 17 per cent in 2019), Pakistan (from 2 per cent to 4 per cent) and Serbia (up from 4 per cent to 7 per cent).
Where did the findings come from ?
The biggest-ever study of attitudes towards vaccines, covering more than 280,000 people in 149 countries, was published in The Lancet.
Set up a decade ago with international funding, the Vaccine Confidence Project carries out surveys to monitor “vaccine hesitancy” – public scepticism about vaccination described by the World Health Organisation in 2019 as one of the ten biggest threats to global health.
What did the study find ?
The comparison showed that confidence in the safety and effectiveness of vaccines is low in many countries, including Japan, Russia and much of Europe.
Active hostility to vaccination is also emerging in some, including Indonesia, Nigeria, Pakistan and Serbia.
However, contrary to widespread belief, the survey found that confidence in vaccination has generally risen in the United States in recent years, despite publicity given to “anti-vaxxer” campaigns. Levels of confidence in the UK have also remained relatively high.
What drives such wide-ranging views?
Uptake of vaccines was most consistently linked to confidence in their benefits, trust in information from health-care workers rather than family and friends, better science education and belonging to younger age-groups. Income and religion were found to be relatively weakly linked to uptake, although minority religious groups tended to be more likely to be sceptical.
What are the implications of the study?
The survey found attitudes towards vaccines are extremely fluid, and can quickly change for the worse as the result of a local scare.
The researchers cite the surge in vaccine scepticism in the Philippines between 2015 and 2018 following concerns about a vaccine against dengue fever.
Reports of the deaths of children led to the vaccine being withdrawn – prompting widespread scepticism about vaccines in general. A similar scare about the HPV vaccine has led to Japan remaining deeply sceptical about vaccination, with social media spreading the concern globally.
What does it mean for Covid-19 vaccines ?
According to the researchers, the results underline the need for governments to monitor attitudes towards vaccinations and act swiftly to combat scepticism.
“What stood out was the volatility and the ups and downs,” said Prof Heidi Larson, director of the Vaccines Confidence Project. “High uptake does not mean it will stay that way.
“It is vital with new and emerging disease threats such as the Covid-19 pandemic, that we regularly monitor public attitudes to quickly identify countries and groups with declining confidence, so we can help guide where we need to build trust to optimise uptake of new life-saving vaccines”, she said.
Experts must combat misinformation to reassure public
“One of the main threats to the resilience of vaccination programmes globally is the rapid and global spread of misinformation," said Dr Larson.
"When there is a large drop in vaccination coverage, it is often because there's an unproven vaccine safety scare seeding doubt and distrust.
"Sometimes there is a genuine small risk that gets rapidly spread and amplified to appear to be a much larger risk.
"There are also cases where vaccine debates have been purposefully polarised, exploiting the doubting public and system weaknesses for political purposes, while waning vaccine confidence in other places may be influenced by a general distrust in government and scientific elites.”
Co-lead author of the study, Clarissa Simas, said it fell to experts to ensure members of the public had access to accurate information.
"The public seem to generally understand the value of vaccines, but the scientific and public health community needs to do much better at building public trust in the safety of vaccination, particularly with the hope of a Covid-19 vaccine," she said.
According to the latest findings by the team, not published in the new paper, attitudes towards a Covid-19 vaccine have changed in the UK since the outbreak started.
At the end of March, when fears about the pandemic were starting to peak, only 5 per cent of those asked said they would decline vaccination. Yet by June, with daily cases of Covid-19 rapidly declining, the proportion saying they would not be vaccinated had tripled to 15 per cent.
According to Prof Larson, the global VCP survey has identified which countries need to make the most effort to combat vaccine hesitancy: “It needs to start yesterday,” she said.
Robert Matthews is visiting professor of science at Aston University, Birmingham, UK
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Trump v Khan
2016: Feud begins after Khan criticised Trump’s proposed Muslim travel ban to US
2017: Trump criticises Khan’s ‘no reason to be alarmed’ response to London Bridge terror attacks
2019: Trump calls Khan a “stone cold loser” before first state visit
2019: Trump tweets about “Khan’s Londonistan”, calling him “a national disgrace”
2022: Khan’s office attributes rise in Islamophobic abuse against the major to hostility stoked during Trump’s presidency
July 2025 During a golfing trip to Scotland, Trump calls Khan “a nasty person”
Sept 2025 Trump blames Khan for London’s “stabbings and the dirt and the filth”.
Dec 2025 Trump suggests migrants got Khan elected, calls him a “horrible, vicious, disgusting mayor”
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The Vile
Starring: Bdoor Mohammad, Jasem Alkharraz, Iman Tarik, Sarah Taibah
Director: Majid Al Ansari
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You Were Never Really Here
Director: Lynne Ramsay
Starring: Joaquim Phoenix, Ekaterina Samsonov
Four stars
PROFILE OF CURE.FIT
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Founders: Mukesh Bansal and Ankit Nagori
Based: Bangalore, India
Sector: Health & wellness
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Investment: $250 million
Investors: Accel, Oaktree Capital (US); Chiratae Ventures, Epiq Capital, Innoven Capital, Kalaari Capital, Kotak Mahindra Bank, Piramal Group’s Anand Piramal, Pratithi Investment Trust, Ratan Tata (India); and Unilever Ventures (Unilever’s global venture capital arm)
Tour de France Stage 16:
165km run from Le Puy-en-Velay to Romans-sur-Isère
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Education: Bachelors degree in mechanical engineering
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Favourite place in the UAE: Downtown Dubai
Favourite book: A Life in Administration by Ghazi Al Gosaibi.
First owned baking book: How to Be a Domestic Goddess by Nigella Lawson.
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Name: Mamo
Year it started: 2019 Founders: Imad Gharazeddine, Asim Janjua
Based: Dubai, UAE
Number of employees: 28
Sector: Financial services
Investment: $9.5m
Funding stage: Pre-Series A Investors: Global Ventures, GFC, 4DX Ventures, AlRajhi Partners, Olive Tree Capital, and prominent Silicon Valley investors.
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Our Time Has Come
Alyssa Ayres, Oxford University Press
World record transfers
1. Kylian Mbappe - to Real Madrid in 2017/18 - €180 million (Dh770.4m - if a deal goes through)
2. Paul Pogba - to Manchester United in 2016/17 - €105m
3. Gareth Bale - to Real Madrid in 2013/14 - €101m
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5. Gonzalo Higuain - to Juventus in 2016/17 - €90m
6. Neymar - to Barcelona in 2013/14 - €88.2m
7. Romelu Lukaku - to Manchester United in 2017/18 - €84.7m
8. Luis Suarez - to Barcelona in 2014/15 - €81.72m
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10. James Rodriguez - to Real Madrid in 2014/15 - €75m
Pari
Produced by: Clean Slate Films (Anushka Sharma, Karnesh Sharma) & KriArj Entertainment
Director: Prosit Roy
Starring: Anushka Sharma, Parambrata Chattopadhyay, Ritabhari Chakraborty, Rajat Kapoor, Mansi Multani
Three stars
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Results
5pm: Maiden (PA) Dh80,000 (Turf) 1,600m; Winner: Rawat Al Reef, Adrie de Vries (jockey), Abdallah Al Hammadi (trainer)
5.30pm: Wathba Stallions Cup Handicap (PA) Dh70,000 (T) 1,400m; Winner: Noof KB, Richard Mullen, Ernst Oertel
6pm: Handicap (PA) Dh80,000 (T) 1,200m; Winner: AF Seven Skies, Bernardo Pinheiro, Qaiss Aboud
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7pm: UAE Arabian Derby – Prestige (PA) Dh150,000 (T) 2,200m; Winner: Dergham Athbah, Richard Mullen, Mohamed Daggash
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8pm: Abu Dhabi Championship – Group 3 (TB) Dh380,000 (T) 2,200m; Winner: Irish Freedom, Antonio Fresu, Satish Seemar