Manchester United will have to subdue another potential giant-killer after the 11-time FA Cup winners were handed a fourth round trip to League Two minnows Cambridge United in Monday's draw.
Louis van Gaal’s team were paired with the lowest ranked team left in the FA Cup and will head to the tiny Abbey Stadium on the weekend of January 24-25.
A total of 79 league places separate Richard Money’s side with Van Gaal’s star-studded line-up, who were able to avoid an embarrassing third round defeat at League One outfit Yeovil Town on Sunday as they cruised to a 2-0 win.
Holders Arsenal, 2-0 winners against last season’s beaten finalists Hull City in the third round on Sunday, will also be hoping to avoid an upset when they travel to Championship team Brighton & Hove Albion.
Manchester City host Championship promotion contenders Middlesbrough after coming from behind to win 2-1 against Sheffield Wednesday, another second tier team, on Sunday.
Premier League leaders Chelsea could face a feisty London derby against Millwall at Stamford Bridge if they come through their replay with Bradford City.
Jose Mourinho’s men will be heavy favourites to advance whether they face Championship strugglers Millwall or League One promotion chasers Bradford, although Millwall knocked Chelsea out of the FA Cup in 1995 and 1985.
Liverpool, 2-1 winners over AFC Wimbledon on Monday, will host Bolton Wanderers as they continue their bid to say farewell to departing captain Steven Gerrard with a Wembley victory.
Gerrard, who announced last week that he will leave Anfield at the end of the season, turns 35 on the day of the FA Cup final – which would be his final match for Liverpool if they make it.
Sheffield United’s reward for their shock 3-0 win over QPR on Sunday is a trip to fellow third tier side Preston North End.
Draw for the fourth round of the English FA Cup made on Monday:
Southampton/Ipswich Town v Crystal Palace
Cambridge United v Manchester United
Blackburn Rovers v Swansea City
Chelsea v Millwall/Bradford City
Derby County v Scunthorpe/Chesterfield
Preston North End v Sheffield United
Birmingham City v West Bromwich Albion
Aston Villa v AFC Bournemouth
Cardiff City v Reading
Liverpool v Bolton Wanderers
Burnley/Tottenham v Leicester City
Brighton v Arsenal
Rochdale v Stoke City
Sunderland v Fulham/Wolves
Doncaster/Bristol City v Everton/West Ham United
Manchester City v Middlesbrough
*Ties to be played across the weekend beginning January 24.
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