Singers Jennifer Lopez and HER will star in a new multi-artist concert to raise money for Covid-19 vaccines.
Vax Live: The Concert to Reunite the World will be streamed across the world, as well as broadcast on limited TV networks, on May 8.
It follows in the footsteps of last year's One World: Together at Home fundraiser, in which locked-down stars including Lady Gaga performed from their homes.
Vax Live will be hosted by singer Selena Gomez and also feature the Foo Fighters, J Balvin and Eddie Vedder, according to organiser Global Citizen, an international advocacy group.
"This is really an opportunity to call on world leaders to make sure that the 27 million heroic healthcare workers around the world that don't yet have access to a vaccine can get access over the coming months," said Global Citizen chief executive Hugh Evans.
The concert will air on TV channels ABC, CBS and Fox, as well as on iHeartMedia radio stations and YouTube.
"This is a historic moment to encourage people around the world to take the Covid-19 vaccine when it becomes available to them, call on world leaders to share vaccine doses equitably and to bring people together for a night of music in a way that hasn't felt possible in the past year," Gomez said. "I can't wait to be a part of it."
The event will also campaign for fair and equal access to vaccines for all, urging nations to donate excess doses and give financial support to the Covax facility, backed by the World Health Organisation and the Global Alliance for Vaccines and Immunisation.
Covax aims to secure two billion vaccine doses for lower-income countries by the end of 2021.
"The great news is there have already been many nations around the world that are starting to donate doses," Evans said. "Australia, for example, donated a million doses to Papua New Guinea. We know the Norwegian government decided to make a donation of doses.
"There's really great momentum that is building," he added.