The 2018 Nobel Prize in Chemistry was awarded on Wednesday to US scientist, Frances Arnold plus the Anglo-American duo, George Smith and Gregory Winter for pioneering work on evolutionary science.
The fifth woman to win the Nobel Prize in chemistry, Dr Arnold was credited in 1993 with performing the first directed evolution of enzymes -- proteins that catalyse chemical reactions -- that are now used to manufacture everything from biofuels to pharmaceuticals.
Dr Smith developed a method, known as phage display, in which a virus that infects bacteria can be used to evolve new proteins. Dr Winter later used phage display to produce new pharmaceuticals.
“This year’s Nobel Laureates in chemistry have been inspired by the power of evolution and used the same principles — genetic change and selection — to develop proteins that solve mankind’s chemical problems,” the Royal Swedish Academy of Sciences said in a statement on awarding the $1 million prize.
Among the applications of the directed evolution of enzymes are more environmentally-friendly chemical manufacturing to produce substances such as renewable fuels for greener transport systems.
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The phage technology was used for the directed evolution of antibodies and the first one based on phage display was approved in 2002 and is used for rheumatoid arthritis, psoriasis and inflammatory bowel diseases.
The anti-bodies created through this chemical process have the potential to neutralise toxins, counteract autoimmune diseases and cure metastatic cancer.
Last year’s Nobel Prize for chemistry was awarded to Jaques Dubochet, Joachim Frank and Richard Henderson for developing a new way to assemble precise three-dimensional images of biological molecules like proteins, DNA and RNA. Their work helped scientists decipher processes within cells that were previously invisible, leading to better understanding of viruses like Zika.
The years Ramadan fell in May
The line up
Friday: Giggs, Sho Madjozi and Masego
Saturday: Nas, Lion Bbae, Roxanne Shante and DaniLeigh
Sole DXB runs from December 6 to 8 at Dubai Design District. Weekend pass is Dh295 while a one day pass is Dh195. Tickets are available from www.soledxb.com
UAE athletes heading to Paris 2024
Equestrian
Abdullah Humaid Al Muhairi, Abdullah Al Marri, Omar Al Marzooqi, Salem Al Suwaidi, and Ali Al Karbi (four to be selected).
Judo
Men: Narmandakh Bayanmunkh (66kg), Nugzari Tatalashvili (81kg), Aram Grigorian (90kg), Dzhafar Kostoev (100kg), Magomedomar Magomedomarov (+100kg); women's Khorloodoi Bishrelt (52kg).
Cycling
Safia Al Sayegh (women's road race).
Swimming
Men: Yousef Rashid Al Matroushi (100m freestyle); women: Maha Abdullah Al Shehi (200m freestyle).
Athletics
Maryam Mohammed Al Farsi (women's 100 metres).
THREE POSSIBLE REPLACEMENTS
Khalfan Mubarak
The Al Jazira playmaker has for some time been tipped for stardom within UAE football, with Quique Sanchez Flores, his former manager at Al Ahli, once labelling him a “genius”. He was only 17. Now 23, Mubarak has developed into a crafty supplier of chances, evidenced by his seven assists in six league matches this season. Still to display his class at international level, though.
Rayan Yaslam
The Al Ain attacking midfielder has become a regular starter for his club in the past 15 months. Yaslam, 23, is a tidy and intelligent player, technically proficient with an eye for opening up defences. Developed while alongside Abdulrahman in the Al Ain first-team and has progressed well since manager Zoran Mamic’s arrival. However, made his UAE debut only last December.
Ismail Matar
The Al Wahda forward is revered by teammates and a key contributor to the squad. At 35, his best days are behind him, but Matar is incredibly experienced and an example to his colleagues. His ability to cope with tournament football is a concern, though, despite Matar beginning the season well. Not a like-for-like replacement, although the system could be adjusted to suit.
Herc's Adventures
Developer: Big Ape Productions
Publisher: LucasArts
Console: PlayStation 1 & 5, Sega Saturn
Rating: 4/5