Nothing separates the pair in the standings ahead of Sunday's season finale, with the Mercedes driver and Red Bull race tied on 369.5 points.
It means whoever finishes highest will be crowned the 2021 F1 world champion.
Should both Hamilton and Verstappen crash out, Verstappen will win the title by dint of having won more races this season (9-8).
Friday's first practice session is from 1-2.30pm with the evening session at 5pm UAE time.
Be sure to check out our coverage of the build up, including:
- Abu Dhabi to host Grand Prix until 2030 after signing extension with F1
- F1 issues ban warning to Hamilton and Verstappen if any trouble at Abu Dhabi GP
- Race to Abu Dhabi: How Hamilton and Verstappen arrive at Yas neck and neck
- Hamilton and Verstappen rule out clear-the-air talks ahead of Abu Dhabi GP