The experimental test has a false-positive rate of 0.5 per cent. Getty
The experimental test has a false-positive rate of 0.5 per cent. Getty
The experimental test has a false-positive rate of 0.5 per cent. Getty
The experimental test has a false-positive rate of 0.5 per cent. Getty

Experimental blood test can detect more than 50 cancers early


Simon Rushton
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A blood test capable of detecting more than 50 types of cancer before symptoms appear will soon be used to screen for the disease, oncology scientists announced on Friday.

The Grail system, developed in the US, will be piloted in England in the autumn after positive assessments of its accuracy, particularly in the detection of lung and bowel cancers, they said.

The experimental blood test can detect cancer often before any clinical signs or symptoms and has a very low false-positive rate, said the team's report, published in the journal Annals of Oncology.

Dr Marco Gerlinger, from London's Institute of Cancer Research, said the “impressive” results offered a glimpse into the future of medicine.

“False positives are low, which is important, as this will avoid misdiagnoses. For some of the most common tumour types, such as bowel or lung cancer, the test even picked up cancers that were very small, at a stage where many of them could potentially be cured.

“The study was done in patients whose cancer was already diagnosed based on other tests and this screening technology still needs to be tested in actual screening trials before routine use,” he said.

“But it already allows a glance at early cancer detection in the future which will almost certainly be built around liquid biopsy tests, which detect cancer DNA in the bloodstream.”

In the most recent trial, of 2,823 people with the disease and 1,254 people without, the new test correctly identified cancer in 51.5 per cent of cases across all stages of the disease, with a false-positive rate of 0.5 per cent.

In the UK, the test could help meet the National Health Service’s goal of increasing the proportion of cancers caught early, which could be the key to reducing cancer mortality.

“These data suggest that, if used alongside existing screening tests, the multi-cancer detection test could have a profound impact on how cancer is detected and, ultimately, on public health.”

The test was able to detect a range of cancers including head and neck, ovarian, pancreatic, oesophageal and some blood.

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AI traffic lights to ease congestion at seven points to Sheikh Zayed bin Sultan Street

The seven points are:

Shakhbout bin Sultan Street

Dhafeer Street

Hadbat Al Ghubainah Street (outbound)

Salama bint Butti Street

Al Dhafra Street

Rabdan Street

Umm Yifina Street exit (inbound)

Ten tax points to be aware of in 2026

1. Domestic VAT refund amendments: request your refund within five years

If a business does not apply for the refund on time, they lose their credit.

2. E-invoicing in the UAE

Businesses should continue preparing for the implementation of e-invoicing in the UAE, with 2026 a preparation and transition period ahead of phased mandatory adoption. 

3. More tax audits

Tax authorities are increasingly using data already available across multiple filings to identify audit risks. 

4. More beneficial VAT and excise tax penalty regime

Tax disputes are expected to become more frequent and more structured, with clearer administrative objection and appeal processes. The UAE has adopted a new penalty regime for VAT and excise disputes, which now mirrors the penalty regime for corporate tax.

5. Greater emphasis on statutory audit

There is a greater need for the accuracy of financial statements. The International Financial Reporting Standards standards need to be strictly adhered to and, as a result, the quality of the audits will need to increase.

6. Further transfer pricing enforcement

Transfer pricing enforcement, which refers to the practice of establishing prices for internal transactions between related entities, is expected to broaden in scope. The UAE will shortly open the possibility to negotiate advance pricing agreements, or essentially rulings for transfer pricing purposes. 

7. Limited time periods for audits

Recent amendments also introduce a default five-year limitation period for tax audits and assessments, subject to specific statutory exceptions. While the standard audit and assessment period is five years, this may be extended to up to 15 years in cases involving fraud or tax evasion. 

8. Pillar 2 implementation 

Many multinational groups will begin to feel the practical effect of the Domestic Minimum Top-Up Tax (DMTT), the UAE's implementation of the OECD’s global minimum tax under Pillar 2. While the rules apply for financial years starting on or after January 1, 2025, it is 2026 that marks the transition to an operational phase.

9. Reduced compliance obligations for imported goods and services

Businesses that apply the reverse-charge mechanism for VAT purposes in the UAE may benefit from reduced compliance obligations. 

10. Substance and CbC reporting focus

Tax authorities are expected to continue strengthening the enforcement of economic substance and Country-by-Country (CbC) reporting frameworks. In the UAE, these regimes are increasingly being used as risk-assessment tools, providing tax authorities with a comprehensive view of multinational groups’ global footprints and enabling them to assess whether profits are aligned with real economic activity. 

Contributed by Thomas Vanhee and Hend Rashwan, Aurifer

Real estate tokenisation project

Dubai launched the pilot phase of its real estate tokenisation project last month.

The initiative focuses on converting real estate assets into digital tokens recorded on blockchain technology and helps in streamlining the process of buying, selling and investing, the Dubai Land Department said.

Dubai’s real estate tokenisation market is projected to reach Dh60 billion ($16.33 billion) by 2033, representing 7 per cent of the emirate’s total property transactions, according to the DLD.

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