Aug 13, 2018; Mason, OH, USA; John Isner (USA) returns a shot against Sam Querrey (USA) in the Western and Southern tennis open at Lindner Family Tennis Center. Mandatory Credit: Aaron Doster-USA TODAY Sports
John Isner's best run at the US Open was a quarter-final spot in 2011. Reuters

That losing feeling: John Isner leads list of American men looking to end 15-year US Open drought




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