Sanofi is investing €610 million at two French sites to turn them into a hub for vaccine research. Alamy
Sanofi is investing €610 million at two French sites to turn them into a hub for vaccine research. Alamy
Sanofi is investing €610 million at two French sites to turn them into a hub for vaccine research. Alamy
Sanofi is investing €610 million at two French sites to turn them into a hub for vaccine research. Alamy

France to ramp up medicine production amid Covid-19 crisis


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France's president and top drugmaker announced plans on Tuesday to bolster domestic production of medicines as countries scramble to strengthen their healthcare industries to counter the coronavirus pandemic.

Drugmaker Sanofi, which is working on two potential coronavirus vaccines, said it would invest €610 million ($679m/Dh2.5 billion) at two French sites to turn them into a hub dedicated to research, development and production of vaccines.

Speaking at the Marcy-L'Etoile facility, president Emmanuel Macron also pledged €200m to help domestic research and manufacturing of medicines and said his government would announce plans on Thursday to bring back some drug production facilities to France.

"Everybody saw that during this crisis some commonly used drugs were no longer produced in France and Europe. So we must no longer just ask questions, but draw the conclusions," Mr Macron said at the Sanofi site near Lyon, central France.

There are currently no approved treatments or vaccines for Covid-19, the illness caused by the new coronavirus which has killed more than 431,000 globally. Drugmakers across the world are rushing to address that, while governments in turn are jostling to try to ensure they will be in line for supplies.

The issue has become particularly sensitive in France after Sanofi chief executive Paul Hudson signalled in May that Europe was being too slow in supporting work on a vaccine and hinted US patients might get any vaccine it develops first, given Washington had provided more funding.

Although Sanofi quickly back-pedalled, promising a vaccine would be made available worldwide simultaneously, the comments raised alarm over Europe's lack of coordination.

In the latest sign European countries are now trying to catch up, a group formed by France, Germany, Italy and the Netherlands struck a deal on Saturday to secure 400 million doses of AstraZeneca's potential vaccine.

The European Commission, meanwhile, received a mandate from EU governments on Friday to negotiate advance purchases of up to six vaccines using proceeds of an emergency fund of €2.4bn.

Mr Macron cited paracetamol as one of the drugs he wanted to see fully produced in France again. The last European plant making the active ingredient for the common painkiller was shut in 2008, but governments have become increasingly worried about relying on imports after India, one of the biggest producers of drug ingredients, banned exports at the start of the pandemic.

Bringing production home may be a complicated process, industry players have warned, reversing a years-long strategy by drugmakers sources abroad to free up capital and escape countries like France where costs are high and labour laws tough.

Studies say up to 80 per cent of the active pharmaceutical ingredients used by European drugmakers are produced outside of the region, mostly in India and China.

Mr Macron also said he hoped to strike a deal with Sanofi in the coming days to reserve supplies of its potential Covid-19 vaccines, without giving details.

Final stage clinical trials of Sanofi's vaccines - one in partnership with Britain's GlaxoSmithKline, the other with US company Translate Bio - are expected to start by the end of this year or the beginning of 2021.

Mr Macron is due to hold a virtual meeting with heads of several drugmakers later on Tuesday. Hudson and officials from Pfizer, Johnson & Johnson and Moderna among others are expected to take part.

As part of its investment plan, Sanofi will spend €490m over five years to build a new facility at Neuville-sur-Saone to produce three to four vaccines at once, rather than just one at the moment. Some 200 new jobs are expected, the company said.

Sanofi will also commit €120m to a new research centre at Marcy-l'Etoile to develop vaccines for emerging diseases.

Mercer, the investment consulting arm of US services company Marsh & McLennan, expects its wealth division to at least double its assets under management (AUM) in the Middle East as wealth in the region continues to grow despite economic headwinds, a company official said.

Mercer Wealth, which globally has $160 billion in AUM, plans to boost its AUM in the region to $2-$3bn in the next 2-3 years from the present $1bn, said Yasir AbuShaban, a Dubai-based principal with Mercer Wealth.

Within the next two to three years, we are looking at reaching $2 to $3 billion as a conservative estimate and we do see an opportunity to do so,” said Mr AbuShaban.

Mercer does not directly make investments, but allocates clients’ money they have discretion to, to professional asset managers. They also provide advice to clients.

“We have buying power. We can negotiate on their (client’s) behalf with asset managers to provide them lower fees than they otherwise would have to get on their own,” he added.

Mercer Wealth’s clients include sovereign wealth funds, family offices, and insurance companies among others.

From its office in Dubai, Mercer also looks after Africa, India and Turkey, where they also see opportunity for growth.

Wealth creation in Middle East and Africa (MEA) grew 8.5 per cent to $8.1 trillion last year from $7.5tn in 2015, higher than last year’s global average of 6 per cent and the second-highest growth in a region after Asia-Pacific which grew 9.9 per cent, according to consultancy Boston Consulting Group (BCG). In the region, where wealth grew just 1.9 per cent in 2015 compared with 2014, a pickup in oil prices has helped in wealth generation.

BCG is forecasting MEA wealth will rise to $12tn by 2021, growing at an annual average of 8 per cent.

Drivers of wealth generation in the region will be split evenly between new wealth creation and growth of performance of existing assets, according to BCG.

Another general trend in the region is clients’ looking for a comprehensive approach to investing, according to Mr AbuShaban.

“Institutional investors or some of the families are seeing a slowdown in the available capital they have to invest and in that sense they are looking at optimizing the way they manage their portfolios and making sure they are not investing haphazardly and different parts of their investment are working together,” said Mr AbuShaban.

Some clients also have a higher appetite for risk, given the low interest-rate environment that does not provide enough yield for some institutional investors. These clients are keen to invest in illiquid assets, such as private equity and infrastructure.

“What we have seen is a desire for higher returns in what has been a low-return environment specifically in various fixed income or bonds,” he said.

“In this environment, we have seen a de facto increase in the risk that clients are taking in things like illiquid investments, private equity investments, infrastructure and private debt, those kind of investments were higher illiquidity results in incrementally higher returns.”

The Abu Dhabi Investment Authority, one of the largest sovereign wealth funds, said in its 2016 report that has gradually increased its exposure in direct private equity and private credit transactions, mainly in Asian markets and especially in China and India. The authority’s private equity department focused on structured equities owing to “their defensive characteristics.”

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