Omicron sub-strain has greater growth rate and may be more transmissible

UK scientists say BA.2 mutation is now more dominant than is predecessor

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A strain of Omicron that is being monitored by experts has a greater growth rate than the original version and transmission of it among household contacts is likely to be higher, the UK Health Security Agency (UKHSA) has said.

The BA. 2 strain is a sub-lineage of the now dominant original Omicron variant known as BA.1.

Last week, it was designated as a “variant under investigation” and on Friday UKHSA said that as of January 24, there had been 1,072 confirmed cases identified in England.

The agency said that BA. 2 had an increased growth rate compared to BA. 1, where there were enough cases to assess it.

It added that while growth rates can be overestimated in early analyses of a new variant, “the apparent growth advantage is currently substantial”.

Contact tracing analysis suggests that between December 27 and January 11, transmission was likely to be higher among contacts of BA. 2 cases in households at 13.4 per cent than those for contacts of other Omicron cases (10.3 per cent).

But the agency said that the findings should be interpreted with caution as early findings can change quickly when new variants are identified.

A preliminary assessment found no evidence that vaccines would be any less effective against symptomatic disease for BA.2.

There is currently no data on the severity of the strain.

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Dr Susan Hopkins, chief medical adviser for UKHSA, said: “We now know that BA. 2 has an increased growth rate which can be seen in all regions in England.

“We have also learnt that BA. 2 has a slightly higher secondary attack rate than BA. 1 in households.

“Although hospitalisations and deaths remain low, cases are still high in some areas and some age groups so it’s important that we continue to act cautiously as restrictions are lifted.

“Consider wearing a face covering when in crowded places. Take a vaccine to protect yourself against Covid-19. If you have any symptoms, take a test.”

Jonathan Ball, professor of molecular virology at the University of Nottingham, said: “It’s still early days, but the evidence so far suggests that BA. 2 may be more transmissible than its close relative Omicron.

“However, the key issues are whether this variant is associated with more severe disease and if it can escape immunity delivered by vaccines.

“Early indicators suggest that the vaccines will provide similar levels of protection as we have seen for Omicron, so this is good news.

“Whether or not it causes more severe disease will become apparent as more data is collected.”

Updated: January 28, 2022, 8:50 PM