Arabidopsis thaliana is under investigation at a university in the Netherlands for possibly flouting Darwinism by passing acquired traits to its offspring.
Arabidopsis thaliana is under investigation at a university in the Netherlands for possibly flouting Darwinism by passing acquired traits to its offspring.

Biology waxes as physics wanes



As college students settle in to another year of study, those taking science courses may want to check out the September 6th issue of Science – and ask themselves if they’ve made the right choice.

The journal’s content of is a bellwether of the health of the subject. And to judge by two back-to-back articles in its pages earlier this month, those wanting to be where the action is may want to consider switching to biology, where a revolution could be about to break.

In recent years physics has been seen as the place to be, with its city-sized atom smashers, billion-dollar space probes and literally cosmic ambition. Its theories encompass everything from the workings of the atom to the origin of the universe and underpin every gadget and gizmo.

Yet all is not well on the frontier. Despite their best efforts, physicists are running out of big new ideas.

In a sense they are victims of their own success. Theorists have spent decades assembling a mathematical account of the subatomic particles and forces between them, known as the Standard Model. Meanwhile, experimentalists have been putting it to the test in machines such as the 27km-long Large Hadron Collider near Geneva.

And the good news is that the theory has passed every test – culminating last year in the discovery of the Higgs boson, which may well lead to Nobel Prizes next month.

The bad news is that physicists were hoping for more. They wanted the LHC to give them some hints about what lies beyond the Standard Model, which for all its successes is known to be incomplete.

For example, it says nothing about the force of gravity, nor about the driving force of the entire cosmos, known as Dark Energy, or the most common form of mass in the universe, Dark Matter.

The LHC has found nothing to help the theorists with these riddles. Indeed, it has made things worse by ruling out some ideas they had for creating the “Theory of Everything”.

As the Science piece glumly reports, it is a similar story at the other end of the size scale. Astrophysicists are celebrating confirmation of their basic theories about the cosmos by their equivalent of the LHC, the orbiting Planck telescope.

By examining the radiation left over from the Big Bang, Planck supports the long-standing idea that the universe began about 13.8 billion years ago with a brief period of so-called inflation, resulting in a mix of matter and energy that has been expanding ever since.

But like the LHC, Planck has given theorists no clues about what drove that inflation, or why the universe is now filled with enigmatic Dark Energy and Dark Matter.

Many physicists now fear they are entering a long fallow period, unable to squeeze anything new out of their nice, neat but underpowered theories.

Yet over in biology departments, things are looking much brighter. The second piece in Science describes how biologists are facing the realisation that Darwin may not be the final word in evolution.

It reports on packed sessions at this year’s Congress of the European Society for Evolutionary Biology in Lisbon, Portugal, where researchers learnt of results apparently backing a notorious rival theory to Darwinian evolution.

First put forward over 200 years ago by the French naturalist Jean Lamarck, it claims that living organisms can inherit traits acquired by their forebears during their lifetime.

According to Lamarck, giraffes acquired their long neck from antelope forebears, who spent their lives stretching up to eat leaves on trees.

In contrast, Darwinism sees all such traits as the result of random mutation of genes that just happen to prove useful to survival, and thus have a higher chance of being passed on to offspring. The idea of genes being permanently affected by life events is regarded as ludicrous.

Yet while it is clear that genes affect cells and thus the resulting organisms, there have long been hints of the reverse happening as well. One example is diet: we can choose to alter what we eat, and thus what ends up in our cells – which in turn can affect genetically related traits.

About 20 per cent of people carry a genetic trait that boosts their risk of heart attacks by up to 60 per cent. In 2011, researchers showed that the lethal effect of this gene could be switched off by changing diet to one rich in raw fruit and vegetables.

But Lamarckism goes a step further than this “epigenetic” effect. It posits that organisms can influence not only the action of their own genes, but of those of their offspring too.

Now evidence for this is beginning to emerge, as scientists cramming into those meetings in Lisbon heard last month.

A team led by Dr Frank Johannes at the University of Groningen in the Netherlands has been looking for Lamarck-like effects in a plant called Arabidopsis thaliana.

A relative of cabbage, A thalianais has a genome that is both relatively small and thoroughly known, making it an ideal genetic test bed.

The team set about creating multiple generations of the plant to see if they could spawn genetically identical strains with permanently altered traits.

And they appear to have succeeded. In results unveiled at the meeting, the team announced the emergence of strains with different heights and flowering times that have persisted through eight generations – despite them all having the same genes.

This suggests that epigenetic effects can persist down the generations. Given that such effects can be triggered by the environment or even the organism itself, this would mean Lamarck’s ideas cannot be dismissed after all.

Not surprisingly, many researchers are demanding further evidence before accepting this contradiction of Darwin’s idea. Is there perhaps something odd about A thaliana that makes it a rare exception?

For biologists, confirmation of these findings could prove as momentous as the events that struck physics almost a century ago, when studies of a solar eclipse showed that Newton’s law of gravity was just an approximation to the larger truth revealed by Einstein.

In fact, given the likely role of epigenetics in so many human traits, the effect of what was unveiled in Lisbon last month may prove even more momentous.

O Robert Matthews is visiting reader in science at Aston University, Birmingham, England

The biog

Siblings: five brothers and one sister

Education: Bachelors in Political Science at the University of Minnesota

Interests: Swimming, tennis and the gym

Favourite place: UAE

Favourite packet food on the trip: pasta primavera

What he did to pass the time during the trip: listen to audio books

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Why are you, you?
From this question, a new beginning.
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For you are a world, and a meeting of worlds.
Our dream is to unite that which has been
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A great story unites us all,
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Why are you, you?
Because we are mirrors of each other.
Because together we create new worlds.
Together we are more powerful than we know.
We connect, we inspire, we multiply illuminations
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Aggro Dr1ft

Director: Harmony Korine
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What it means to be a conservationist

Who is Enric Sala?

Enric Sala is an expert on marine conservation and is currently the National Geographic Society's Explorer-in-Residence. His love of the sea started with his childhood in Spain, inspired by the example of the legendary diver Jacques Cousteau. He has been a university professor of Oceanography in the US, as well as working at the Spanish National Council for Scientific Research and is a member of the World Economic Forum’s Global Future Council on Biodiversity and the Bio-Economy. He has dedicated his life to protecting life in the oceans. Enric describes himself as a flexitarian who only eats meat occasionally.

What is biodiversity?

According to the United Nations Environment Programme, all life on earth – including in its forests and oceans – forms a “rich tapestry of interconnecting and interdependent forces”. Biodiversity on earth today is the product of four billion years of evolution and consists of many millions of distinct biological species. The term ‘biodiversity’ is relatively new, popularised since the 1980s and coinciding with an understanding of the growing threats to the natural world including habitat loss, pollution and climate change. The loss of biodiversity itself is dangerous because it contributes to clean, consistent water flows, food security, protection from floods and storms and a stable climate. The natural world can be an ally in combating global climate change but to do so it must be protected. Nations are working to achieve this, including setting targets to be reached by 2020 for the protection of the natural state of 17 per cent of the land and 10 per cent of the oceans. However, these are well short of what is needed, according to experts, with half the land needed to be in a natural state to help avert disaster.

Multitasking pays off for money goals

Tackling money goals one at a time cost financial literacy expert Barbara O'Neill at least $1 million.

That's how much Ms O'Neill, a distinguished professor at Rutgers University in the US, figures she lost by starting saving for retirement only after she had created an emergency fund, bought a car with cash and purchased a home.

"I tell students that eventually, 30 years later, I hit the million-dollar mark, but I could've had $2 million," Ms O'Neill says.

Too often, financial experts say, people want to attack their money goals one at a time: "As soon as I pay off my credit card debt, then I'll start saving for a home," or, "As soon as I pay off my student loan debt, then I'll start saving for retirement"."

People do not realise how costly the words "as soon as" can be. Paying off debt is a worthy goal, but it should not come at the expense of other goals, particularly saving for retirement. The sooner money is contributed, the longer it can benefit from compounded returns. Compounded returns are when your investment gains earn their own gains, which can dramatically increase your balances over time.

"By putting off saving for the future, you are really inhibiting yourself from benefiting from that wonderful magic," says Kimberly Zimmerman Rand , an accredited financial counsellor and principal at Dragonfly Financial Solutions in Boston. "If you can start saving today ... you are going to have a lot more five years from now than if you decide to pay off debt for three years and start saving in year four."

If you go

There are regular flights from Dubai to Kathmandu. Fares with Air Arabia and flydubai start at Dh1,265.
In Kathmandu, rooms at the Oasis Kathmandu Hotel start at Dh195 and Dh120 at Hotel Ganesh Himal.
Third Rock Adventures offers professionally run group and individual treks and tours using highly experienced guides throughout Nepal, Bhutan and other parts of the Himalayas.

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Titan Sports Academy:

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Sunday

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The Sky Is Pink

Director: Shonali Bose

Cast: Priyanka Chopra Jonas, Farhan Akhtar, Zaira Wasim, Rohit Saraf

Three stars

COMPANY PROFILE

Name: SmartCrowd
Started: 2018
Founder: Siddiq Farid and Musfique Ahmed
Based: Dubai
Sector: FinTech / PropTech
Initial investment: $650,000
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Investors: Various institutional investors and notable angel investors (500 MENA, Shurooq, Mada, Seedstar, Tricap)

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MATCH INFO

Manchester United 1 (Rashford 36')

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UAE medallists at Asian Games 2023

Gold
Magomedomar Magomedomarov – Judo – Men’s +100kg
Khaled Al Shehi – Jiu-jitsu – Men’s -62kg
Faisal Al Ketbi – Jiu-jitsu – Men’s -85kg
Asma Al Hosani – Jiu-jitsu – Women’s -52kg
Shamma Al Kalbani – Jiu-jitsu – Women’s -63kg
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Bishrelt Khorloodoi – Judo – Women’s -52kg
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Mohamed Al Suwaidi – Jiu-jitsu – Men’s -69kg
Balqees Abdulla – Jiu-jitsu – Women’s -48kg
Bronze
Hawraa Alajmi – Karate – Women’s kumite -50kg
Ahmed Al Mansoori – Cycling – Men’s omnium
Abdullah Al Marri – Equestrian – Individual showjumping
Team UAE – Equestrian – Team showjumping
Dzhafar Kostoev – Judo – Men’s -100kg
Narmandakh Bayanmunkh – Judo – Men’s -66kg
Grigorian Aram – Judo – Men’s -90kg
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Saeed Al Kubaisi – Jiu-jitsu – Men’s -85kg
Shamsa Al Ameri – Jiu-jitsu – Women’s -57kg

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Started: June 2022
Founder: Mohammed Alnamara
Based: Dubai
Sector: Microfinance
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Investors: Family offices

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Company name: Hayvn
Started: 2018
Founders: Christopher Flinos, Ahmed Ismail
Based: Abu Dhabi, UAE
Sector: financial
Initial investment: undisclosed
Size: 44 employees
Investment stage: series B in the second half of 2023
Investors: Hilbert Capital, Red Acre Ventures

Company profile

Company name: Fasset
Started: 2019
Founders: Mohammad Raafi Hossain, Daniel Ahmed
Based: Dubai
Sector: FinTech
Initial investment: $2.45 million
Current number of staff: 86
Investment stage: Pre-series B
Investors: Investcorp, Liberty City Ventures, Fatima Gobi Ventures, Primal Capital, Wealthwell Ventures, FHS Capital, VN2 Capital, local family offices

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Europa League final

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Greizmann (21', 49'), Gabi (89')

AUSTRALIA SQUADS

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Twenty20 squad: Aaron Finch (captain), Sean Abbott, Ashton Agar, Alex Carey, Pat Cummins, Mitchell Marsh, Glenn Maxwell, Jhye Richardson, Kane Richardson, Steve Smith, Mitchell Starc, Matthew Wade, David Warner, Adam Zampa

The years Ramadan fell in May

1987

1954

1921

1888

COMPANY PROFILE

Name: DarDoc
Based: Abu Dhabi
Founders: Samer Masri, Keswin Suresh
Sector: HealthTech
Total funding: $800,000
Investors: Flat6Labs, angel investors + Incubated by Hub71, Abu Dhabi's Department of Health
Number of employees: 10

RIVER SPIRIT

Author: Leila Aboulela 

Publisher: Saqi Books

Pages: 320

Available: Now